Project Abstract
Dissolved oxygen (DO) is an important parameter with significant effect on cellular development and function. Micro-scale laminar flow and hydrodynamic focusing provide ideal tools for the generation of controlled chemical micro-environments and their application as stimuli to cells. Building upon the DO sensor patterning process and flow control devices developed in the Department for Electrical and Computer Engineering, a new family of Lab-on-a-Chip type devices capable of controlling and measuring the cellular oxygen micro-environment will be developed.