My research interests are related to studying the structure and function of proteins, the aim being to obtain a better understanding of key biological questions at level of atoms and molecules.
My research interests encompass the following areas:
-Understanding proteins from microbial pathogens, especially those involved in essential metabolic pathways or otherwise important for pathogenicity, bacterial survival and anti-microbial resistance (e.g. proteins from the TB-causing bacteria M.tuberculosis (M.tb) and the opportunistic pathogen S. aureus).
The aim being to understand not only the role of these proteins in the bacteria and disease, but also uses structural information to design inhibitors that could become future drugs to treat microbial
-Understanding the molecular basis and communication networks behind protein cooperativty and allostery
-Bio-engineering proteins to act as tools in a range of applications