UC Research Profile - University of Canterbury

Dr Anna S Mitchell

Contact

Department: School of Psychology, Speech and Hearing

Email: anna.mitchell@canterbury.ac.nz

Direct Dial: +64 3 3691562

Office:

Languages: English, New Zealand Sign Language (NZSL)

About

Research / Creative works

Fields of Research

Learning
Memory
Decision-making
Spatial navigation
Dementias
Neuropathology
Neurodevelopmental disorders

Researcher Summary

Brain networks support our everyday activities, from learning and remembering information to making decisions and finding our way around in our environment. My research focuses on how the brain is processing information to allow us to carry out these higher cognitive abilities so that we may understand what happens in the brain when learning, decision-making and remembering no longer occur or we lose our ability to find our way around.

Subject Area: Disciplines

Psychology: Behavioural Science ; Cognitive Psychology ; Neuroscience ; Psychology

Research/Scholarly/Creative Works

Hartig R., Klink PC., Polyakova Z., Dehaqani M-RA., Bondar I., Merchant H., Vanduffel W., Roe AW., Nambu A. and Thirumala M. (2023) A framework and resource for global collaboration in non-human primate neuroscience.. Curr Res Neurobiol 4: 100079. http://dx.doi.org/10.1016/j.crneur.2023.100079. (Journal Articles)

Jain AK., Tansey G., Hartig R., Mitchell AS. and Basso MA. (2023) Trends and Treatment Approaches for Complications in Neuroscience Experiments with Monkey Species. Comparative Medicine 73(3): 216-228. http://dx.doi.org/10.30802/AALAS-CM-22-000079. (Journal Articles)

Janssen P., Isa T., Lanciego J., Leech K., Logothetis N., Poo M-M. and Mitchell AS. (2023) Visualizing advances in the future of primate neuroscience research.. Curr Res Neurobiol 4: 100064. http://dx.doi.org/10.1016/j.crneur.2022.100064. (Journal Articles)

Lomi E., Jeffery KJ. and Mitchell AS. (2023) Convergence of location, direction, and theta in the rat anteroventral thalamic nucleus. iScience 26(7) http://dx.doi.org/10.1016/j.isci.2023.106993. (Journal Articles)

Perry BAL., Mendez JC. and Mitchell AS. (2023) Cortico-thalamocortical interactions for learning, memory and decision-making. Journal of Physiology 601(1): 25-35. http://dx.doi.org/10.1113/JP282626. (Journal Articles)

Ainsworth M., Wu Z., Browncross H., Mitchell AS., Bell AH. and Buckley MJ. (2022) Frontopolar cortex shapes brain network structure across prefrontal and posterior cingulate cortex. Progress in Neurobiology 217 http://dx.doi.org/10.1016/j.pneurobio.2022.102314. (Journal Articles)

Mendez JC., Perry BAL., Heppenstall RJ., Mason S. and Mitchell AS. (2022) Openness about animal research increases public support. Nature Neuroscience 25(4): 401-403. http://dx.doi.org/10.1038/s41593-022-01039-z. (Journal Articles)

Milham M., Petkov C., Belin P., Ben Hamed S., Evrard H., Fair D., Fox A., Froudist-Walsh S., Hayashi T. and Kastner S. (2022) Toward next-generation primate neuroscience: A collaboration-based strategic plan for integrative neuroimaging. In Neuron 110(1): 16-20. http://dx.doi.org/10.1016/j.neuron.2021.10.015. (Conference Contributions - Published)

Ouhaz Z., Perry BAL., Nakamura K. and Mitchell AS. (2022) Mediodorsal Thalamus Is Critical for Updating during Extradimensional Shifts But Not Reversals in the Attentional Set-Shifting Task. eNeuro 9(2) http://dx.doi.org/10.1523/ENEURO.0162-21.2022. (Journal Articles)

Petkov CI., Flecknell P., Murphy K., Basso MA., Mitchell AS., Hartig R. and Thompson-Iritani S. (2022) Unified ethical principles and an animal research 'Helsinki' declaration as foundations for international collaboration.. Curr Res Neurobiol 3: 100060. http://dx.doi.org/10.1016/j.crneur.2022.100060. (Journal Articles)

Homberg JR., Adan RAH., Alenina N., Asiminas A., Bader M., Beckers T., Begg DP., Blokland A., Burger ME. and van Dijk G. (2021) The continued need for animals to advance brain research. Neuron 109(15): 2374-2379. http://dx.doi.org/10.1016/j.neuron.2021.07.015. (Journal Articles)

Klink PC., Aubry JF., Ferrera VP., Fox AS., Froudist-Walsh S., Jarraya B., Konofagou EE., Krauzlis RJ., Messinger A. and Mitchell AS. (2021) Combining brain perturbation and neuroimaging in non-human primates. NeuroImage 235 http://dx.doi.org/10.1016/j.neuroimage.2021.118017. (Journal Articles)

Lomi E., Mathiasen ML., Cheng HY., Zhang N., Aggleton JP., Mitchell AS. and Jeffery KJ. (2021) Evidence for two distinct thalamocortical circuits in retrosplenial cortex. Neurobiology of Learning and Memory 185 http://dx.doi.org/10.1016/j.nlm.2021.107525. (Journal Articles)

Mitchell AS., Hartig R., Basso MA., Jarrett W., Kastner S. and Poirier C. (2021) International primate neuroscience research regulation, public engagement and transparency opportunities. NeuroImage 229 http://dx.doi.org/10.1016/j.neuroimage.2020.117700. (Journal Articles)

Perry BAL., Lomi E. and Mitchell AS. (2021) Thalamocortical interactions in cognition and disease: The mediodorsal and anterior thalamic nuclei. Neuroscience and Biobehavioral Reviews 130: 162-177. http://dx.doi.org/10.1016/j.neubiorev.2021.05.032. (Journal Articles)

Perry BAL., Mason S., Nacef J., Waddle A., Hynes B., Bergmann C., Schmid MC., Petkov CI., Thiele A. and Mitchell AS. (2021) Protective cranial implant caps for macaques. Journal of Neuroscience Methods 348 http://dx.doi.org/10.1016/j.jneumeth.2020.108992. (Journal Articles)

Milham M., Petkov CI., Margulies DS., Schroeder CE., Basso MA., Belin P., Fair DA., Fox A., Kastner S. and Mars RB. (2020) Accelerating the Evolution of Nonhuman Primate Neuroimaging. In Neuron 105(4): 600-603. http://dx.doi.org/10.1016/j.neuron.2019.12.023. (Conference Contributions - Published)

Pelekanos V., Premereur E., Mitchell DJ., Chakraborty S., Mason S., Lee ACH. and Mitchell AS. (2020) Corticocortical and thalamocortical changes in functional connectivity and white matter structural integrity after reward-guided learning of visuospatial discriminations in Rhesus monkeys. Journal of Neuroscience 40(41): 7887-7901. http://dx.doi.org/10.1523/JNEUROSCI.0364-20.2020. (Journal Articles)

Bridge H., Bell AH., Ainsworth M., Sallet J., Premereur E., Ahmed B., Mitchell AS., Schüffelgen U., Buckley M. and Tendler BC. (2019) Preserved extrastriate visual network in a monkey with substantial, naturally occurring damage to primary visual cortex. eLife 8 http://dx.doi.org/10.7554/eLife.42325. (Journal Articles)

Chakraborty S., Ouhaz Z., Mason S. and Mitchell AS. (2019) Macaque parvocellular mediodorsal thalamus: dissociable contributions to learning and adaptive decision-making. European Journal of Neuroscience 49(8): 1041-1054. http://dx.doi.org/10.1111/ejn.14078. (Journal Articles)

Mason S., Premereur E., Pelekanos V., Emberton A., Honess P. and Mitchell AS. (2019) Effective chair training methods for neuroscience research involving rhesus macaques (Macaca mulatta). Journal of Neuroscience Methods 317: 82-93. http://dx.doi.org/10.1016/j.jneumeth.2019.02.001. (Journal Articles)

Perry BAL. and Mitchell AS. (2019) Considering the evidence for anterior and laterodorsal thalamic nuclei as higher order relays to cortex. Frontiers in Molecular Neuroscience 12 http://dx.doi.org/10.3389/fnmol.2019.00167. (Journal Articles)

Ainsworth M., Browncross H., Mitchell DJ., Mitchell AS., Passingham RE., Buckley MJ., Duncan J. and Bell AH. (2018) Functional reorganisation and recovery following cortical lesions: A preliminary study in macaque monkeys. Neuropsychologia 119: 382-391. http://dx.doi.org/10.1016/j.neuropsychologia.2018.08.024. (Journal Articles)

Mitchell AS., Czajkowski R., Zhang N., Jeffery K. and Nelson AJD. (2018) Retrosplenial cortex and its role in spatial cognition.. Brain Neurosci Adv 2: 2398212818757098. http://dx.doi.org/10.1177/2398212818757098. (Journal Articles)

Mitchell AS., Thiele A., Petkov CI., Roberts A., Robbins TW., Schultz W. and Lemon R. (2018) Continued need for non-human primate neuroscience research. Current Biology 28(20): R1186-R1187. http://dx.doi.org/10.1016/j.cub.2018.09.029. (Journal Articles)

Ouhaz Z., Fleming H. and Mitchell AS. (2018) Cognitive functions and neurodevelopmental disorders involving the prefrontal cortex and mediodorsal thalamus. Frontiers in Neuroscience 12(FEB) http://dx.doi.org/10.3389/fnins.2018.00033. (Journal Articles)

Pergola G., Danet L., Pitel AL., Carlesimo GA., Segobin S., Pariente J., Suchan B., Mitchell AS. and Barbeau EJ. (2018) The Regulatory Role of the Human Mediodorsal Thalamus. Trends in Cognitive Sciences 22(11): 1011-1025. http://dx.doi.org/10.1016/j.tics.2018.08.006. (Journal Articles)

Sherman SM., Mason CA., Atabay KD., Kaas JH., LaMantia A-S., Mitchell A. and Walsh C. (2017) Rainer (Ray) W. Guillery 28 August 1929-7 April 2017. European Journal of Neuroscience 46(3): 1933-1936. http://dx.doi.org/10.1111/ejn.13639. (Journal Articles)

Buckley MJ. and Mitchell AS. (2016) Retrosplenial Cortical Contributions to Anterograde and Retrograde Memory in the Monkey. Cerebral Cortex 26(6): 2905-2918. http://dx.doi.org/10.1093/cercor/bhw054. (Journal Articles)

Chakraborty S., Kolling N., Walton ME. and Mitchell AS. (2016) Critical role for the mediodorsal thalamus in permitting rapid reward-guided updating in stochastic reward environments. eLife 5(MAY2016) http://dx.doi.org/10.7554/eLife.13588. (Journal Articles)

Mitchell DJ., Bell AH., Buckley MJ., Mitchell AS., Sallet J. and Duncan J. (2016) A putative multiple-demand system in the macaque brain. Journal of Neuroscience 36(33): 8574-8585. http://dx.doi.org/10.1523/JNEUROSCI.0810-16.2016. (Journal Articles)

Browning PGF., Chakraborty S. and Mitchell AS. (2015) Evidence for mediodorsal thalamus and prefrontal cortex interactions during cognition in macaques. Cerebral Cortex 25(11): 4519-4534. http://dx.doi.org/10.1093/cercor/bhv093. (Journal Articles)

Kwok SC., Mitchell AS. and Buckley MJ. (2015) Adaptability to changes in temporal structure is fornix-dependent. Learning and Memory 22(8): 354-359. http://dx.doi.org/10.1101/lm.038851.115. (Journal Articles)

Mitchell AS. (2015) The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making. Neuroscience and Biobehavioral Reviews 54: 76-88. http://dx.doi.org/10.1016/j.neubiorev.2015.03.001. (Journal Articles)

Ouhaz Z., Ba-M'hamed S., Mitchell AS., Elidrissi A. and Bennis M. (2015) Behavioral and cognitive changes after early postnatal lesions of the rat mediodorsal thalamus. Behavioural Brain Research 292: 219-232. http://dx.doi.org/10.1016/j.bbr.2015.06.017. (Journal Articles)

Rafal RD., Koller K., Bultitude JH., Mullins P., Ward R., Mitchell AS. and Bell AH. (2015) Connectivity between the superior colliculus and the amygdala in humans and macaque monkeys: Virtual dissection with probabilistic DTI tractography. Journal of Neurophysiology 114(3): 1947-1962. http://dx.doi.org/10.1152/jn.01016.2014. (Journal Articles)

Mitchell AS., Murray Sherman S., Sommer MA., Mair RG., Vertes RP. and Chudasama Y. (2014) Advances in understanding mechanisms of thalamic relays in cognition and behavior. Journal of Neuroscience 34(46): 15340-15346. http://dx.doi.org/10.1523/JNEUROSCI.3289-14.2014. (Journal Articles)

Noonan MAP., Sallet J., Mars RB., Neubert FX., O'Reilly JX., Andersson JL., Mitchell AS., Bell AH., Miller KL. and Rushworth MFS. (2014) A Neural Circuit Covarying with Social Hierarchy in Macaques. PLoS Biology 12(9) http://dx.doi.org/10.1371/journal.pbio.1001940. (Journal Articles)

Mitchell AS. and Chakraborty S. (2013) What does the mediodorsal thalamus do? Frontiers in Systems Neuroscience (JUL) http://dx.doi.org/10.3389/fnsys.2013.00037. (Journal Articles)

O'Reilly JX., Croxson PL., Jbabdi S., Sallet J., Noonan MP., Mars RB., Browning PGF., Wilson CRE., Mitchell AS. and Miller KL. (2013) Causal effect of disconnection lesions on interhemispheric functional connectivity in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America 110(34): 13982-13987. http://dx.doi.org/10.1073/pnas.1305062110. (Journal Articles)

Mars RB., Jbabdi S., Sallet J., O'Reilly JX., Croxson PL., Olivier E., Noonan MAP., Bergmann C., Mitchell AS. and Baxter MG. (2011) Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. Journal of Neuroscience 31(11): 4087-4100. http://dx.doi.org/10.1523/JNEUROSCI.5102-10.2011. (Journal Articles)

Baxter MG., Gaffan D., Kyriazis DA. and Mitchell AS. (2009) Ventrolateral prefrontal cortex is required for performance of a strategy implementation task but not reinforcer devaluation effects in rhesus monkeys. European Journal of Neuroscience 29(10): 2049-2059. http://dx.doi.org/10.1111/j.1460-9568.2009.06740.x. (Journal Articles)

Baxter MG., Browning PGF. and Mitchell AS. (2008) Perseverative interference with object-in-place scene learning in rhesus monkeys with bilateral ablation of ventrolateral prefrontal cortex (Learning and Memory (2008) 15 (126-132)). Learning and Memory 15(4): 189. (Journal Articles)

Baxter MG., Browning PGF. and Mitchell AS. (2008) Perseverative interference with object-in-place scene learning in rhesus monkeys with bilateral ablation of ventrolateral prefrontal cortex. Learning and Memory 15(3): 126-132. http://dx.doi.org/10.1101/lm.804508. (Journal Articles)

Baxter MG., Gaffan D., Kyriazis DA. and Mitchell AS. (2008) Dorsolateral prefrontal lesions do not impair tests of scene learning and decision-making that require frontal-temporal interaction. European Journal of Neuroscience 28(3): 491-499. http://dx.doi.org/10.1111/j.1460-9568.2008.06353.x. (Journal Articles)

Mitchell AS. and Gaffan D. (2008) The magnocellular mediodorsal thalamus is necessary for memory acquisition, but not retrieval. Journal of Neuroscience 28(1): 258-263. http://dx.doi.org/10.1523/JNEUROSCI.4922-07.2008. (Journal Articles)

Mitchell AS., Browning PGF., Wilson CRE., Baxter MG. and Gaffan D. (2008) Dissociable roles for cortical and subcortical structures in memory retrieval and acquisition. Journal of Neuroscience 28(34): 8387-8396. http://dx.doi.org/10.1523/JNEUROSCI.1924-08.2008. (Journal Articles)

Baxter MG., Gaffan D., Kyriazis DA. and Mitchell AS. (2007) Orbital prefrontal cortex is required for object-in-place scene memory but not performance of a strategy implementation task. Journal of Neuroscience 27(42): 11327-11333. http://dx.doi.org/10.1523/JNEUROSCI.3369-07.2007. (Journal Articles)

Mitchell AS., Baxter MG. and Gaffan D. (2007) Dissociable performance on scene learning and strategy implementation after lesions to magnocellular mediodorsal thalamic nucleus. Journal of Neuroscience 27(44): 11888-11895. http://dx.doi.org/10.1523/JNEUROSCI.1835-07.2007. (Journal Articles)

Mitchell AS., Browning PGF. and Baxter MG. (2007) Neurotoxic lesions of the medial mediodorsal nucleus of the thalamus disrupt reinforcer devaluation effects in rhesus monkeys. Journal of Neuroscience 27(42): 11289-11295. http://dx.doi.org/10.1523/JNEUROSCI.1914-07.2007. (Journal Articles)

Wilson CRE., Gaffan D., Mitchell AS. and Baxter MG. (2007) Neurotoxic lesions of ventrolateral prefrontal cortex impair object-in-place scene memory. European Journal of Neuroscience 25(8): 2514-2522. http://dx.doi.org/10.1111/j.1460-9568.2007.05468.x. (Journal Articles)

Mitchell AS. and Dalrymple-Alford JC. (2006) Lateral and anterior thalamic lesions impair independent memory systems. Learning & Memory 13(3): 388-396. (Journal Articles)

Mitchell AS. and Dalrymple-Alford JC. (2005) Dissociable Memory Effects after Medial Thalamus Lesions. European Journal of Neuroscience 22: 973-985. (Journal Articles)

Mitchell A. and Dalrymple-Alford JC. (2001) Spatial working memory and the brainstem cholinergic innervation to the anteroventral thalamus. . (Journal Articles)