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Dr Simone Dimartino

Contact

Department: Chemical and Process Engineering

Email: simone.dimartino@canterbury.ac.nz

Office:

Languages: English, French, Italian, Portuguese, Spanish

About
Research / Creative works
Supervision
Methods & Equipment

Fields of Research

  • Characterization and functionalization of chromatographic materials
  • Mathematical modeling of transport phenomena in chromatographic media
  • Affinity chromatography for the primary capture step in downstream processing
  • Convective media for chromatographic separations
  • Wet resistant adhesives and bio-compatible adhesives
  • Protein adsoption on surfaces
  • Material characterization using Fourier Transform Infrared Sectroscopy
  • Study of marine organisms for the development of bio-inspired glues

Researcher Summary

3D printing of adsorptive media:
In this research we aim to create adsorptive porous media using 3D printing technologies. Current adsorptive media present irregular pores and random interconnections, resulting in product variability and sub-optimal performance. Fine control of the packing geometry is achieved using 3D printing. This idea is currently employed to generate porous media for chromatographic applications, but the same approach could be used in a range of industries in the chemical engineering arena.

Novel chromatographic stationary phases for bio-separations:
I am interested in alternative chromatographic stationary phases for the purification of large biomolecules. These chromatographic media are necessary to overcome cost and performance limitations of actual bead based resins. Channelled-Capillary Polymeric fibres are currently considered, a packing constituted of fibres collinearly entangled to give micron-sized parallel tube-like channels. These structures allow for very efficient fluid flow and low backpressure.

Wet-resistant bio-inspired adhesives:
Wet resistant adhesives have direct implications in biomedical applications. This project finds inspiration from NZ native seaweed to develop underwater adhesive. The present research activities focus on the chemical, structural and mechanical characterization of the adhesive secreted by one of the strongest seaweed in the word, Durvillaea antarctica, and its weaker “sister”, Hormosira banksii.

Subject Area: Disciplines

  • Biology: Ecology, Evolution and Behaviour: Marine Ecology
  • Engineering and Technology: Bioengineering; Bioprocess Engineering; Materials; Separation Processes
  • Biology: Molecular, Cellular and Whole Organism Biology: Biomolecular Interactions

Resources

  • BIC Research Theme

Research/Scholarly/Creative Works

  • Dimartino S., Nawada S., Dolamore F., Gordon A., Rezanavaz R., Huber T., Clucas D. and Fee CJ. (2016) Experimental and computational evaluation of new designs for 3D printed chromatography media. Salzburg, Austria: International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016, 6-9 Nov 2016. (Conference Contributions - Other)
  • Fee CJ., Newberry F., Gordon A., Wilson P., Moyers-Gonzales M., Murray R., Huber T. and Dimartino S. (2016) Optimization of porous bed geometric features to maximize adsorption of proteins and passage of suspended solids in a 3D-printed adsorption column. Philadelphia, PA, USA: PREP Symposium 2016, 18-21 Jul 2016. (Conference Contributions - Other)
  • Fee CJ., Newberry F., Gordon A., Wilson PL., Moyers-Gonzalez M., Murray R., Huber T. and Dimartino S. (2016) 3D-printed chromatography columns for downstream capture of proteins in the presence of suspended cells. Phuket, Thailand: 2nd Bioprocess Asia Conference, 5-8 Dec 2016. (Conference Contributions - Other)
  • Gordon A., Fee CJ., Dimartino S., Nawada S., Huber T. and Clucas D. (2016) 3D-Printed Agarose Cation-Exchange Monoliths for Protein Capture from Solids-Laden Feeds. Bermuda: Recovery of Biological Products XVII. (Oral Presentations)
  • Nawada S., Dolamore F., Dimartino S. and Fee CJ. (2016) Triply Periodic Minimal Surfaces as Stationary Phase Microstructures. Philadelphia, PA, USA: 29th International Symposium on Preparative and Process Chromatography (PREP 2016), 17-20 Jul 2016. (Conference Contributions - Other)
  • Nawada S., Dolamore F., Fee CJ. and Dimartino S. (2016) 3D printing of chromatography media: closing the loop between real word experiments and computer simulations. San Francisco, CA, USA: 44th International Symposium on High Performance Liquid Phase Separations and Related Technologies (HPLC 2016), 19-24 Jun 2016. (Conference Contributions - Other)
  • Chandrasekaran N., Dimartino S., Janmale T., Gieseg SP. and Fee CJ. (2015) Adsorption of chemically synthesized mussel adhesive peptide sequences containing DOPA on stainless steel. Journal of Peptide Science 21(8): 630-635. http://dx.doi.org/10.1002/psc.2776. (Journal Articles)
  • Dimartino S., Boi C. and Sarti GC. (2015) Scale-up of affinity membrane modules: comparison between lumped and physical models. Journal of Molecular Recognition 28(3): 180-190. http://dx.doi.org/10.1002/jmr.2406. (Journal Articles)
  • Dimartino S., Mather AV., Alestra T., Nawada S. and Haber M. (2015) Experimental and Computational Analysis of a Novel Flow Channel to Assess the Adhesion Strength of Sessile Marine Organisms. Sydney, Australia: 24th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 7-10 Apr 2015. (Conference Contributions - Other)
  • Dolamore F., Dimartino S. and Fee CJ. (2015) Computational Fluid Dynamic Studies of Novel 3D Printed Chromatography Columns. Wellington, New Zealand: 2015 BioProcessing Network Conference, 21-22 Sep 2015. (Conference Contributions - Other)
  • Fee C., Dimartino S., Clucas D., Huber T., Nawada S., Dolamore F., Gordon A. and Rezanavaz R. (2015) Disrupting The Packed Bed: 3D Printing of Chromatography Columns. Philadelphia, PA, USA: 28th Symposium on Preparative and Process Chromatography (PREP 2015), 26-29 Jul 2015. (Conference Contributions - Other)
  • Fee CJ., Dimartino S., Nawada S., Huber T., Clucas D., Dolamore F., Gordon A. and Vilmay M. (2015) 3D Printed Resins: a novel alternative to pre-packed chromatography columns? Munich, Germany: Downstream Processing World Congress, 24-25 Feb 2015. (Conference Contributions - Other)
  • Gordon A., Dimartino S. and Fee CJ. (2015) Factors influencing 1,1'-carbonyldiimidazole activation of cross-linked agarose and subsequent ligand coupling for chromatography stationary phases. Wellington, New Zealand: 2015 BioProcessing Network Conference, 21-22 Sep 2015. (Conference Contributions - Other)
  • Herigstad MO., Dimartino S., Boi C. and Sarti GC. (2015) Experimental characterization of the transport phenomena, adsorption, and elution in a protein A affinity monolithic medium. Journal of Chromatography A (1407): 130-138. http://dx.doi.org/10.1016/j.chroma.2015.06.045. (Journal Articles)
  • Huber T., Dimartino S. and Fee CJ. (2015) Cross-linked all-cellulose composite hydrogels made from aqueous NaOH/urea solutions. Sydney, Australia: 24th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE). (Oral Presentations)
  • Huber T., Dimartino S. and Fee CJ. (2015) The effect of physical and chemical cross-linking on cellulose hydrogels made from aqueous NaOH/urea solutions. Stockholm, Sweden: European Advanced Materials Congress 2016. (Oral Presentations)
  • Huber T., Dimartino S. and Fee CJ. (2015) Cross-linked all-cellulose composite hydrogels made from aqueous NaOH/urea solutions. Sydney, Australia: 24th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 7-10 Apr 2015. (Conference Contributions - Other)
  • Nawada S., Dimartino S., Fee CJ., Huber T. and Clucas D. (2015) Effects of Line Defects in Porous Media Studied through 3D Printing. Wellington, New Zealand: BioProcessing Network Conference, 21-22 Sep 2015. (Conference Contributions - Other)
  • Nawada S., Dimartino S., Fee CJ., Huber T. and Clucas DM. (2015) Effects of Line Defects in Porous Media Studied through 3D Printing. Philadelphia, PA, USA: 28th Symposium on Preparative and Process Chromatography (PREP 2015), 26-29 Jul 2015. (Conference Contributions - Other)
  • Nawada S., Fee CJ. and Dimartino S. (2015) Effects of Particle Shape and Linear Defects in Porous Media Studied through 3D Printing. Wellington, New Zealand: 2015 BioProcessing Network Conference, 21-22 Sep 2015. (Conference Contributions - Other)
  • Rezanavaz R., Dimartino S. and Fee CJ. (2015) Highly Porous "Clickable" Polymer as Stationary Phase for Separation of Biomolecules. Wellington, New Zealand: 2015 BioProcessing Network Conference, 21-22 Sep 2015. (Conference Contributions - Other)
  • Teo A., Dimartino S., Goh KKT., Wen J., Oey I., Ko S., Kwak HS., Golding M. and Lee SJ. (2015) Characterisation of interfacial bi-layer or complex structures of nanoemulsions coated with WPI and lactoferrin studied by Quartz Crystal Microbalance with Dissipation (QCM-D). Palmerston North, New Zealand: New Zealand Institute of Food Science and Technology (NZIFST) Conference 2015, 30 Jun-2 Jul 2015. (Conference Contributions - Other)
  • Boi C., Dimartino S., Herigstad MO., da Sousa Silva J. and Sarti GC. (2014) A comparison between chromatographic stationary phases. Rostock, Germany: 16th Recovery of Biological Products Conference (RXVI), 27-31 Jul 2014. (Conference Contributions - Other)
  • Dimartino S., Fee CJ., Nawada S., Clucas D., Huber T., Gordon A. and Dolamore F. (2014) 3D printing of porous media at the microstructural scale. Rostock, Germany: 16th Recovery of Biological Products Conference (RXVI), 27-31 Jul 2014. (Conference Contributions - Other)
  • Dimartino S., Mather A., Nawada S. and Haber M. (2014) Novel flow chamber for the determination of the attachment strength of marine organisms. Istanbul, Turkey: 2nd International Conference on Biological and Biomimetic Adhesives, 6-9 May 2014. (Conference Contributions - Other)
  • Dimartino S., Mather A., Nawada S., Savory D. and McQuillan AJ. (2014) Comparative study of the bio-adhesives produced from macroalgae. Perth, Australia: Chemeca 2014, 28 Sep-1 Oct 2014. (Conference Contributions - Other)
  • Dimartino S., Mather AV., Alestra T., Nawada S. and Haber M. (2014) Experimental and computational analysis of a novel flow channel to assess the adhesion strength of sessile marine organisms. Interface Focus 5 20140059 http://dx.doi.org/10.1098/rsfs.2014.0059. (Journal Articles)
  • Dimartino S., Savory DM. and McQuillan AJ. (2014) Comparative study of the attachment of Fucales seaweeds from temperate regions of the Southern Hemisphere. Istanbul, Turkey: 2nd International Conference on Biological and Biomimetic Adhesives, 6-9 May 2014. (Conference Contributions - Other)
  • Dimartino S., Savory DM. and McQuillan AJ. (2014) Preparation of biological samples for the study of wet-resistant adhesives inspired by kelps. In. (Conference Contributions - Published)
  • Fee CJ., Nawada S. and Dimartino S. (2014) 3D Printed Porous Media Columns with Fine Control of Column Packing Geometry. Journal of Chromatography A 1333: 18-24. http://dx.doi.org/10.1016/j.chroma.2014.01.043. (Journal Articles)
  • Gordon A., Huber T., Dimartino S. and Fee CJ. (2014) Development and modification of cellulose based hydrogels for chromatography. Melbourne, Australia: BioProcessing Network Conference 2014, 21-23 Oct 2014. (Conference Contributions - Other)
  • Nawada S., Dimartino S. and Fee C. (2014) The effects of bead overlap on chromatographic performance in 3D printed packed bed columns. International Labmate Apr 2014: 18-20. (Journal Articles)
  • Nawada S., Dimartino S. and Fee CJ. (2014) The use of 3D printing in the study of packed bed microstructures. Rostock, Germany: 16th Recovery of Biological Products Conference (RXVI), 27-31 Jul 2014. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2013) Scale up of membrane affinity chromatography processes. San Francisco, CA, USA: American Institute of Chemical Engineers (AIChE) Annual Meeting, 3-8 Nov 2013. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2013) Scale up of membrane affinity chromatography processes. Vienna, Austria: Affinity 2013-20th Biennial Meeting of the International Society for Molecular Recognition, 26-29 Jun 2013. (Conference Contributions - Other)
  • Chandrasekaran N., Dimartino S. and Fee CJ. (2013) Comparative study of dairy protein-associated water and its adsorption effects on stainless steel surfaces by fluorescent labelling and QCM-D. Auckland, New Zealand: New Zealnd Conference of Chemical and Materials Engineering 2013 (NZCCME 2013), 25-26 Nov 2013. (Conference Contributions - Other)
  • Chandrasekaran N., Dimartino S. and Fee CJ. (2013) Study of the adsorption of proteins on stainless steel surfaces using QCM-D. Chemical Engineering Research & Design 91(9): 1674-1683. http://dx.doi.org/10.1016/j.cherd.2013.07.017. (Journal Articles)
  • Dimartino S., Chandrasekaran N. and Fee CJ. (2013) Study of the adsorption of proteins on stainless steel surfaces using QCM-D. In. (Conference Contributions - Published)
  • Dimartino S., Lir I., Haber M. and Azhari R. (2013) Characterization of biomimetic adhesives from the red algae Gracilaria conferta for biomedical applications. In Santos R; Aldred N; Gorb S; Flammang P (Ed.), Biological and Biomimetic Adhesives, Challenges and Opportunities: 117-131. Cambridge: RSC Publishing. http://dx.doi.org/10.1039/9781849737135-00117. (Chapters)
  • Dimartino S., Savory D. and McQuillan AJ. (2013) In situ IR bioadhesion studies of Durvillaea antarctica - sperm, egg, and zygote. Melbourne, Australia: Australia, New Zealand and the Pacific (ANZPAC) Workshop on Biofouling Management for Sustainable Shipping, 5-9 May 2013. (Conference Contributions - Other)
  • Dimartino S., Savory D., Petrone L. and McQuillan AJ. (2013) ATR-FTIR and microscopic study of the attachment of zygotes from Fucoid seaweeds. Cluj Napoca, Romania: Co-operation in Science and Technology (COST) Action TD0906 Biological Adhesives: from Biology to Biomimetics, 9-11 Apr 2013. (Conference Contributions - Other)
  • Fee CJ., Dimartino S. and Nawada S. (2013) 3D Printed Porous Media - Fine Control of Packing Structures for Adsorption, Filtration and Catalysis. Auckland, New Zealand: New Zealand Conference of Chemical and Materials Engineering 2013 (NZCCME 2013), 25-26 Nov 2013. (Conference Contributions - Other)
  • Fee CJ., Dimartino S. and Nawada S. (2013) Printed chromatography media. Boston, MA, USA: 26th International Symposium on Preparative and Process Chromatography (PREP 2013), 14-17 Jul 2013. (Conference Contributions - Other)
  • Fee CJ., Dimartino S. and Nawada S. (2013) Re-Inventing the Packed Bed - Implications of 3D Printing for Chromatography. Boston, MA, USA: 26th International Symposium on Preparative and Process Chromatography (PREP 2013), 14-17 Jul 2013. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2012) Integration of molecular dynamics and experiments to design mimetic affinity membranes. Stowe, VT, USA: 15th Recovery of Biological Products Conference (RXV), 29 Jul-3 Aug 2012. (Conference Contributions - Other)
  • Chandrasekaran N., Dimartino S. and Fee CJ. (2012) Adsorption of proteins on stainless steel surfaces. In. (Conference Contributions - Published)
  • Dimartino S., Boi C. and Sarti GC. (2012) Scale-up of Convective Affinity Chromatography Based on Validated Physical Model. Boston, MA, USA: International Symposium on Preparative and Process Chromatography, 15-18 Jul 2012. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2012) Scale-up of membrane affinity adsorbers based on tested physical model. London, UK: Euromembrane 2012, 23-27 Sep 2012. (Conference Contributions - Other)
  • Dimartino S., Momich D., Schadock-Hewitt AJ., Marcus RK. and Fee CJ. (2012) Chromatographic properties of capillary-channelled polymer fibres for the purification of large biomolecules. Stowe, VT, USA: Recovery of Biological Products XV, 29 Jul-2 Aug 2012. (Conference Contributions - Other)
  • Dimartino S., Savory D., Petrone L. and McQuillan AJ. (2012) ATR-FTIR study of the bio-adhesive produced by the seaweed Hormosira banksii. Lisbon, Portugal: 1st International Conference on Biological and Biomimetic Adhesives, 9-11 May 2012. (Conference Contributions - Other)
  • Randunu KM., Dimartino S. and Marcus RK. (2012) Hydrodynamic evaluation of polypropylene capillary-channeled fibers as a stationary phase in high performance liquid chromatography. Journal of Separations Science 35(23): 3270-3280. http://dx.doi.org/10.1002/jssc.201200523. (Journal Articles)
  • Boi C., Dimartino S. and Sarti GC. (2011) A mathematical model for protein purification with affinity membranes. Minneapolis, MN, USA: American Institute of Chemical Engineers (AIChE) Annual Meeting, 16-21 Oct 2011. (Conference Contributions - Other)
  • Boi C., Dimartino S., Hofer S., Horak J., Williams S., Sarti GC. and Lindner W. (2011) Influence of different spacer arms on Mimetic Ligand A2P and B14 membranes for human IgG purification. Journal of Chromatography B 879(19): 1633-1640. http://dx.doi.org/10.1016/j.jchromb.2011.03.059. (Journal Articles)
  • Boi C., Dimartino S., Hofer S., Horak J., Williams S., Sarti GC. and Lindner W. (2011) Influence of different spacer arms on mimetic ligand A2P and B14 membranes for human IgG purification. Minneapolis, MN, USA: American Institute of Chemical Engineers Annual Meeting (AIChE), 16-21 Oct 2011. (Conference Contributions - Other)
  • Dimartino S. (2011) Biomolecular Interactions on Surfaces: Research for Biotechnology Applications. Modena, Italy. (Oral Presentations)
  • Dimartino S. (2011) Biomolecular Interactions on Surfaces: Research for Biotechnology Applications. University of Queensland, Australia: AIBN General Meeting. (Oral Presentations)
  • Dimartino S., Boi C. and Sarti GC. (2011) A mathematical model for protein purification with affinity membranes. Tavira, Portugal: 19th Biennial Meeting of the International Society for Molecular Recognition (Affinity 2011), 16-19 Jun 2011. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2011) A validated model for protein purification with affinity membranes. Amsterdam, Netherlands: International Congress on Membranes and Membrane processes, ICOM, 23-29 Jul 2011. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2011) A validated model for protein purification with affinity membranes. Berlin, Germany: European Congress of Applied Biotechnology, ECAB, 25-29 Sep 2011. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2011) A validated model for the simulation of protein purification through affinity membrane chromatography. Journal of Chromatography A 1218(13): 1677-1690. http://dx.doi.org/10.1016/j.chroma.2010.11.056. (Journal Articles)
  • Dimartino S., Boi C. and Sarti GC. (2011) Influence of protein adsorption kinetics on breakthrough broadening in membrane affinity chromatography. Journal of Chromatography A 1218(26): 3966-3972. http://dx.doi.org/10.1016/j.chroma.2011.04.062. (Journal Articles)
  • Dimartino S., Chandrasekaran N. and Fee CJ. (2011) Wet-resistant adhesives for inorganic surfaces. Bad Herrenalb, Germany: Biotranformations, 22-25 Aug 2011. (Conference Contributions - Other)
  • Dimartino S., Herigstad MO., Boi C. and Sarti GC. (2011) Experimental evaluation and theoretical analysis of convective affinity adsorbers for chromatographic applications. Amsterdam, Netherlands: International Congress on Membranes and Membrane Processes (ICOM), 23-29 Jul 2011. (Conference Contributions - Other)
  • Dimartino S., Herigstad MO., Boi C. and Sarti GC. (2011) Membrane and monolithic chromatography: An experimental and theoretical analysis to assess their use in large scale applications. Boston, MA, USA: International Symposium on Preparative and Process Chromatography (PREP), 10-13 Jul 2011. (Conference Contributions - Other)
  • Boi C., Dimartino S., Herigstad MO. and Sarti GC. (2010) A Comparison of Convective-Based Alternatives to Packed Bed Affinity Chromatography for the Purification of Monoclonal Antibodies. Salt Lake City, UT, USA: American Institute of Chemical Engineers Annual Meeting (AIChE), 7-12 Nov 2010. (Conference Contributions - Other)
  • Dimartino S. (2010) Bio-mimetic Convective Media for Affinity Chromatography. University of Canterbury, Christchurch, New Zealand: Biomolecular Interaction Center Seminar. (Oral Presentations)
  • Dimartino S., Herigstad MO., Boi C. and Sarti GC. (2010) A validated model for the simulation of convective affinity chromatography processes. Lake Tahoe, CA, USA: 14th Recovery of Biological Products Conference (RXIV), 1-6 Aug 2010. (Conference Contributions - Other)
  • Dimartino S., Herigstad MO., Boi C. and Sarti GC. (2010) Experimental evaluation and theoretical analysis of convective affinity adsorbers for chromatographic applications. Rimini, Italy: 14th International Biotechnology Symposium and Exhibition (IBS), 14-18 Sep 2010. (Conference Contributions - Other)
  • Dimartino S., Herigstad MO., Boi C. and Sarti GC. (2010) Recent insights in the mathematical modelling of membrane affinity chromatography. Bologna, Italy: International Symposium on the Separation of Proteins, Peptides & Polynucleotides (ISPPP), 5-8 Sep 2010. (Conference Contributions - Other)
  • Herigstad MO., Dimartino S., Boi C. and Sarti GC. (2010) Full characterization and modeling of the transport, affinity-adsorption, and elution of IgG in a protein A monolithic column. Salt Lake City, UT, USA: American Institute of Chemical Engineers (AIChE) Annual Meeting, 7-12 Nov 2010. (Conference Contributions - Other)
  • Herigstad MO., Dimartino S., Boi C. and Sarti GC. (2010) Full characterization and modelling of the transport and affinity-adsorption of IgG in a protein A monolithic column. Bologna, Italy: International Symposium on the Separation of Proteins, Peptides & Polynucleotides (ISPPP), 5-8 Sep 2010. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2009) Affinity membranes for antibody purification. Montpellier, France: Euromembrane, 6-10 Sep 2009. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2009) Experimental and theoretical study of membrane adsorbers for the primary capture of protein manufacturing. Washington, DC, USA: 238th American Chemical Society (ACS) National Meeting, 16-20 Aug 2009. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2009) Novel affinity membranes for IgG purification. Nashville, TN, USA: American Institute of Chemical Engineers (AIChE) Annual Meeting, 8-13 Nov 2009. (Conference Contributions - Other)
  • Dimartino S. (2009) Studio Sperimentale e Modellazione della Separazione di Proteine con Membrane di Affinita (Analysis and modelling of protein separation through affinity membranes). Bologna, Italy. Alma Mater Studiorum - Universita di Bologna. (Theses / Dissertations)
  • Dimartino S., Boi C. and Sarti GC. (2009) A simulation model for membrane affinity chromatography. Montpellier, France: Euromembrane, 6-10 Sep 2009. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Analysis of different affinity membranes for the primary capture step in antibody manufacturing. Philadelphia, PA, USA: American Institute of Chemical Engineers Annual Meeting (AIChE), 16-21 Nov 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Developments in Membrane Affinity Chromatography for Monoclonal Antibody Recovery. Honolulu, HI, USA: International Congress on Membranes and Membrane Processes (ICOM), 12-18 Jul 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Experimental and simulation analysis of membrane adsorbers used for the primary capture step in antibody manufacturing. Chemical Engineering Transactions 14: 91-96. (Journal Articles)
  • Boi C., Dimartino S. and Sarti GC. (2008) Experimental and simulation analysis of membrane adsorbers used for the primary capture step in antibody manufacturing. Naples, Italy: Industrial Biotechnology International Conference (IBIC), 8-11 Jun 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Immunoglobulin purification with affinity membranes. Vale do Lobo, Portugal: Engineering With Membranes (EWM), 25-28 May 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Isolamento primario di anticorpi monoclonali con membrane di affinità. Le Castella, Italy: Convegno GRICU 2008, 14-17 Sep 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Mathematical modelling of membranes, membrane units and validation with experimental results for MAT2B and PROD1B.EU AIMs project. (Reports)
  • Boi C., Dimartino S. and Sarti GC. (2008) Membrane adsorbers for the primary capture step in antibody manufacturing. Quebec City, Canada: 13th Recovery of Biological Product Conference (RXIII), 22-27 Jun 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2008) Performance of a New Protein A Affinity Membrane for the Primary Recovery of Antibodies. Biotechnology Progress 24(3): 640-647. http://dx.doi.org/10.1021/bp0704743. (Journal Articles)
  • Boi C., Dimartino S., Carbonell R. and Sarti GC. (2008) Properties of affinity membranes for h-IgG purification. New Orleans, LA, USA: 235th American Chemical Society (ACS) National Meeting, 6-10 Apr 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S., Giovannangelo M., Sarti GC., van de Ven E., Versteeg Bolhuis L. and Borneman Z. (2008) Correlation of material structure and performance for affinity membranes.EU AIMs project. (Reports)
  • Boi C., Dimartino S., Sarti GC., Hofer S. and Lindner W. (2008) Influence of different spacer arms on affinity membranes for human IgG capture. Zurich, Switzerland: Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA), 28 Sep-1 Oct 2008. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2008) Modellazione della separazione di Immunoglobulina G con membrane di affinità (Modelling of the separation of immunoglobulin G using affinity membranes). Le Castella, Italy: Convegno GRICU 2008, 14-17 Sep 2008. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2008) Modellazione della separazione di Immunoglobulina G con membrane di affinità. Le Castella, Italy: Convegno GRI.C.U. 2008, 14-17 Sep 2008. (Conference Contributions - Other)
  • Dimartino S., Boi C. and Sarti GC. (2008) Simulation of membrane affinity chromatography for immunoglobulin capture. Vale do Lobo, Portugal: Engineering With Membranes (EWM), 25-28 May 2008. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2007) Advances in membrane affinity chromatography for the recovery of antibodies. Boston, MA, USA: 234th American Chemical Society National Meeting & Exposition (ACS), 19-23 Aug 2007. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2007) Developments in membrane affinity chromatography for monoclonal antibody recovery. Orlando, FL, USA: International Symposium on the Separation of Proteins, Peptides & Polynucleotides (ISPPP), 21-24 Oct 2007. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2007) Developments in membrane affinity chromatography for monoclonal antibody recovery. Orlando, FL, USA: International Symposium on the Separation of Proteins, Peptides & Polynucleotides (ISPPP), 21-24 Oct 2007. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2007) Mathematical modelling of membranes, membrane units and validation with experimental results for MAT2A and PROD1B.EU AIMs project. (Reports)
  • Boi C., Dimartino S. and Sarti GC. (2007) Modelling and simulation of affinity membrane adsorption. Journal of Chromatography A 1162(1): 24-33. http://dx.doi.org/10.1016/j.chroma.2007.02.008. (Journal Articles)
  • Dimartino S., Boi C. and Sarti GC. (2007) Dynamic characterization of affinity membranes for monoclonal antibodies purification. Salt Lake City, UT, USA: American Institute of Chemical Engineers Annual Meeting (AIChE), 4-9 Nov 2007. (Conference Contributions - Other)
  • Boi C., Dimartino S. and Sarti GC. (2006) Preparation and testing of affinity membranes for the purification of monoclonal antibodies. Innsbruck, Austria: Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA), 15-18 Oct 2006. (Conference Contributions - Other)
  • Boi C., Dimartino S., Sarti GC., van Beijeren P. and Kreis P. (2006) Mathematical modelling of membranes, membrane unit and validation with experimental results.EU AIMs project. (Reports)
  • Boi C., Dimartino S., van Beijeren P. and Sarti GC. (2006) Evaluation of affinity membrane adsorbers for antibody purification. San Francisco, CA, USA: American Institute of Chemical Engineers Annual Meeting (AIChE), 12-17 Nov 2006. (Conference Contributions - Other)
  • Boi C., Sarti G. and Dimartino S. (2006) Binding kinetics of immunoglobulins on affinity membranes. San Francisco, CA, USA: 232nd American Chemical Society (ACS) National Meeting, 10-14 Sep 2006. (Conference Contributions - Other)
  • Dimartino S. (2006) Theoretical Study of Membrane Adsorbers. Department of Biochemical and Chemical Engineering, Universität Dortmund, Germany. (Oral Presentations)
  • Mutter M., Boi C., Dimartino S., Sarti GC., van Beijeren P. and Kreis P. (2006) Analysis of effective performance of MAT1A with PROD1B.EU AIMs project. (Reports)
  • Dimartino S. (2005) Modellazione dell'adsorbimento di proteine su membrane di affinita (Modelling of protein adsorption on affinity membranes). Bologna, Italy. Alma Mater Studiorum - Universita di Bologna. (Theses / Dissertations)

Student Supervision

Displaying all items.
    Current
  • PhD - Chandrasekaran S: Purification of milk proteins through affinity chromatography (2016)
  • PhD - Dolamore F: Simulation and modelling of perfectly ordered chromatrographic media (2016)
  • PhD - Gordon A: Experimental investigation of 3D printed chromatrographic columns (2016)
  • PhD - Nawada S: 3D printing of adsorptive media (2016)
  • PhD - Rezanavaz R: 3D printing of porous materials (2017)
  • Masters - Majumdar N: Nutraceuticals from algae (2016)
  • Masters - Mather A: Marine bioadhesives produced by seaweed (2015)
  • Completed
  • PhD - Chandrasekaran N: Adsorption of proteins on Stainless steel surfaces (2014)

Key Methodologies

  • Fast Protein Liquid Chromatography (FPLC)
  • Aspen Custom Modeler - Aspen Software Package
  • Quartz Cristal Microbalance with Dissipation (QCM-D)
  • Dinamic Light Scattering (DLS)
  • Controlled culture of algal species
  • Attenuated Total Reflection - Fourier Transfor Infrared Spectroscopy (ATR-FTIR)
  • Microscopic and colorimetric methods on biological samples
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