Research/Scholarly/Creative Works

• Bai Y., Lang EJM., Nazmi AR. and Parker EJ. (2019) Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids. Journal of Biological Chemistry 294(13): 4828-4842. http://dx.doi.org/10.1074/jbc.RA118.005220. (Journal Articles)

• Nazmi AR., Muthu M. and Lloyd-Jones G. (2019) Manipulating intradiol dioxygnenases by C-terminus truncation. Enzyme and Microbial Technology 125: 21-28. http://dx.doi.org/10.1016/j.enzmictec.2019.02.007. (Journal Articles)

• Mittelstädt G., Jiao W., Livingstone EK., Moggre GJ., Nazmi AR. and Parker EJ. (2018) A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochemical Journal 475(1): 247-260. http://dx.doi.org/10.1042/BCJ20170762. (Journal Articles)

• Chehab T., Santos NC., Holthenrich A., Koerdt SN., Disse J., Schuberth C., Nazmi AR., Neeft M., Koch H. and Man KNM. (2017) A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Molecular Biology of the Cell 28(12): 1688-1700. http://dx.doi.org/10.1091/mbc.E17-02-0128. (Journal Articles)

• Jiao W., Blackmore NJ., Nazmi AR. and Parker EJ. (2017) Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis. PLoS ONE 12(6) http://dx.doi.org/10.1371/journal.pone.0180052. (Journal Articles)

• Cross PJ., Heyes LC., Zhang S., Nazmi AR. and Parker EJ. (2016) The Functional Unit of Neisseria meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric. PLoS ONE 11(2) http://dx.doi.org/10.1371/journal.pone.0145187. (Journal Articles)

• Mittelstädt G., Moggré GJ., Panjikar S., Nazmi AR. and Parker EJ. (2016) Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail. Protein Science : 1492-1506. http://dx.doi.org/10.1002/pro.2948. (Journal Articles)

• Nazmi AR., Lang EJM., Bai Y., Allison TM., Othman MH., Panjikar S., Arcus VL. and Parker EJ. (2016) Interdomain conformational changes provide allosteric regulation en route to chorismate. Journal of Biological Chemistry 291(42): 21836-21847. http://dx.doi.org/10.1074/jbc.M116.741637. (Journal Articles)

• Blackmore NJ., Nazmi AR., Hutton RD., Webby MN., Baker EN., Jameson GB. and Parker EJ. (2015) Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: An Example of Molecular Symbiosis. The Journal of Biological Chemistry 290: 18187-18198. http://dx.doi.org/10.1074/jbc.M115.638700. (Journal Articles)

• Nazmi AR., Schofield LR., Dobson RCJ., Jameson GB. and Parker EJ. (2014) Destabilization of the Homotetrameric Assembly of 3-Deoxy-d-Arabino-Heptulosonate-7-Phosphate Synthase from the Hyperthermophile Pyrococcus furiosus Enhances Enzymatic Activity. Journal of Molecular Biology 426(3): 656-673. http://dx.doi.org/10.1016/j.jmb.2013.11.008. (Journal Articles)

• Carraher C., Nazmi AR., Newcomb RD. and Kralicek A. (2013) Recombinant expression, detergent solubilisation and purification of insect odorant receptor subunits. Protein expression and purification 90(2): 160-169. http://dx.doi.org/10.1016/j.pep.2013.06.002. (Journal Articles)

• Nazmi AR., Ozorowski G., Pejic M., Whitelegge JP., Gerke V. and Luecke H. (2012) N-terminal acetylation of annexin A2 is required for S100A10 binding. Biological Chemistry http://dx.doi.org/10.1515/hsz-2012-0179. (Journal Articles)

• Heil A., Nazmi AR., Koltzscher M., Poeter M., Austermann J., Assard N., Baudier J., Kaibuchi K. and Gerke V. (2011) S100P is a Novel Interaction Partner and Regulator of IQGAP1. The Journal of Biological Chemistry 286(9): 7227-7238. http://dx.doi.org/10.1074/jbc.M110.135095. (Journal Articles)

• Austermann J., Nazmi AR., Heil A., Fritz G., Kolinski M., Filipek S. and Gerke V. (2009) Generation and characterization of a novel, permanently active S100P mutant. Biochimica et Biophysica Acta 1793(6): 1078-1085. http://dx.doi.org/10.1016/j.bbamcr.2008.11.012. (Journal Articles)

• Austermann J., Nazmi AR., Müller-Tidow C. and Gerke V. (2008) Characterization of the Ca2+ -regulated Ezrin-S100P Interaction and Its Role in Tumor Cell Migration. The Journal of Biological Chemistry 283(43): 29331-29340. http://dx.doi.org/10.1074/jbc.M806145200. (Journal Articles)

• Nazmi AR., Reinisch T. and Hinz HJ. (2008) Calorimetric studies on renaturation by CaCl2 addition of metal-free α-Amylase from Bacillus licheniformis (BLA). Journal of Thermal Analysis and Calorimetry 91(1): 141-149. http://dx.doi.org/10.1007/s10973-007-8405-0. (Journal Articles)

• Nazmi AR. (2006) Biophysical Characterization of hypertheromophilic alpha-amylase from Bacillus licheniformis (BLA). Muenster, Germany. University of Muenster. (Theses / Dissertations)

• Nazmi AR., Reinisch T. and Hinz HJ. (2006) Ca-binding to Bacillus licheniformis alpha-amylase (BLA). Archives of Biochemistry and Biophysics 453(1): 18-25. http://dx.doi.org/10.1016/j.abb.2006.04.004. (Journal Articles)

Review and Refereeing

• Food and Bioproducts Processing ( 2020 - 2022)

Future Research

• Sustainable biopolymers
• Synthetic biology
• Protein structure and function