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    • Research at UC

Dr Anna Howe

Contact

Department: School of Health Sciences

Office:

Language: English

About
Research / Creative works
Projects
Methods & Equipment

Fields of Research

  • Maternal and Child Health
  • Vaccine Preventable Disease
  • Immunisation Coverage
  • Dietary Patterns
  • Body Composition

Researcher Summary

My research mostly uses routinely collected data to answer wide ranging questions looking at improving child health outcomes. My most recent work has been examining vaccine effectiveness, immunisation coverage, and immunisation programme evaluation, and maternal use of pharmaceuticals during pregnancy and child outcomes, all utilising administrative health data.

While vaccines are determined safe and efficacious/effective in overseas studies before being funded here, gaps still exist in confirming this for New Zealand populations. I have been involved in research examining the epidemiology of pneumococcal disease in New Zealand and examining the overall effectiveness of our routine childhood pneumococcal programme. In addition, certain conditions or diseases mean some children are at higher risk of invasive pneumococcal disease, which cause causes significant morbidity and mortality, especially in the young and patients with underlying conditions. While PHARMAC funds additional vaccines for children considered at high-risk of pneumococcal disease, nobody has actually evaluated the effectiveness of this programme in New Zealand, or even if these high-risk individuals are getting the additional funded protection. Our hope is that understandings from this study will help inform actions to improve vaccination rates and inform schedule decisions, in order to help prevent pneumococcal related morbidity and mortality, and potentially reduce inequities experienced by children with chronic and congenital conditions.

Subject Area: Disciplines

  • Health and Health Sciences: Epidemiology; Population health

Research/Scholarly/Creative Works

  • Duque J., Howe AS., Azziz-Baumgartner E. and Petousis-Harris H. (2022) Multi-decade national cohort identifies adverse pregnancy and birth outcomes associated with acute respiratory illness hospitalisations during the influenza season. Influenza and other Respiratory Viruses http://dx.doi.org/10.1111/irv.13063. (Journal Articles)
  • Howe AS., Gauld NJ., Cavadino AY., Petousis-Harris H., Dumble F., Sinclair O. and Grant CC. (2022) Increasing Uptake of Maternal Pertussis Vaccinations through Funded Administration in Community Pharmacies. Vaccines 10(2) http://dx.doi.org/10.3390/vaccines10020150. (Journal Articles)
  • Pointon L., Howe AS., Hobbs M., Paynter J., Gauld N., Turner N. and Willing E. (2022) Evidence of suboptimal maternal vaccination coverage in pregnant New Zealand women and increasing inequity over time: A nationwide retrospective cohort study. Vaccine 40(14): 2150-2160. http://dx.doi.org/10.1016/j.vaccine.2022.02.079. (Journal Articles)
  • Chisholm H., Paynter J., Willing E., Turner N. and Howe AS. (2021) Does the National Immunisation Register stack up? Quantifying accuracy when compared to parent-held health record books. New Zealand Medical Journal 134(1541): 22-32. (Journal Articles)
  • Higgins S., Stoner L., Lubransky A., Howe AS., Wong JE., Black K. and Skidmore P. (2020) Social jetlag is associated with cardiorespiratory fitness in male but not female adolescents. Sleep Medicine 75: 163-170. http://dx.doi.org/10.1016/j.sleep.2020.07.030. (Journal Articles)
  • Howe AS., Pointon L., Gauld N., Paynter J., Willing E. and Turner N. (2020) Pertussis and influenza immunisation coverage of pregnant women in New Zealand. Vaccine 38(43): 6766-6776. http://dx.doi.org/10.1016/j.vaccine.2020.08.030. (Journal Articles)
  • McIlhone KA., Best EJ., Petousis-Harris H. and Howe AS. (2020) Impact of rotavirus vaccine on paediatric rotavirus hospitalisation and intussusception in New Zealand: A retrospective cohort study. Vaccine 38(7): 1730-1739. http://dx.doi.org/10.1016/j.vaccine.2019.12.045. (Journal Articles)
  • Chisholm H., Howe A., Best E. and Petousis-Harris H. (2019) Pertussis vaccination failure in the New Zealand pediatric population: Study protocol. Vaccines 7(3) http://dx.doi.org/10.3390/vaccines7030065. (Journal Articles)
  • Landi SN., Radke S., Boggess K., Engel SM., Stürmer T., Howe AS. and Jonsson Funk M. (2019) Comparative effectiveness of metformin versus insulin for gestational diabetes in New Zealand.. Pharmacoepidemiology and drug safety 28 12: 1609-1619. http://dx.doi.org/10.1002/pds.4907. (Journal Articles)
  • Landi SN., Radke S., Engel SM., Boggess K., Stürmer T., Howe AS. and Funk MJ. (2019) Association of Long-term Child Growth and Developmental Outcomes with Metformin vs Insulin Treatment for Gestational Diabetes. JAMA Pediatrics 173(2): 160-168. http://dx.doi.org/10.1001/jamapediatrics.2018.4214. (Journal Articles)
  • Landi SN., Radke S., Engel SM., Boggess K., Stürmer T., Howe AS. and Funk MJ. (2019) Association of long-term child growth and developmental outcomes with metformin vs insulin treatment for gestational diabetes. Obstetrical and Gynecological Survey 74(7): 392-393. http://dx.doi.org/10.1097/01.ogx.0000569240.11617.23. (Journal Articles)
  • McAuliffe GN., Taylor SL., Moore S., Hewitt J., Upton A., Howe AS. and Best EJ. (2019) Suboptimal performance of rotavirus testing in a vaccinated community population should prompt laboratories to review their rotavirus testing algorithms in response to changes in disease prevalence. Diagnostic Microbiology and Infectious Disease 93(3): 203-207. http://dx.doi.org/10.1016/j.diagmicrobio.2018.10.003. (Journal Articles)
  • Petousis-Harris H., Howe AS., Paynter J., Turner N. and Griffin J. (2019) Pneumococcal conjugate vaccines turning the tide on inequity: A retrospective cohort study of New Zealand Children Born 2006-2015. Clinical Infectious Diseases 68(5): 818-826. http://dx.doi.org/10.1093/cid/ciy570. (Journal Articles)
  • Petousis-Harris H., Jiang Y., Yu L., Watson D., Walls T., Turner N., Howe A. and Griffin J. (2019) Pertussis Immunisation in Pregnancy Safety (PIPS) Study: A Retrospective Cohort Study of Safety Outcomes in Infants Exposed to Tdap Vaccine in Utero. http://dx.doi.org/10.20944/preprints201907.0210.v1. (Journal Articles)
  • Petousis-Harris H., Jiang Y., Yu L., Watson D., Walls T., Turner N., Howe AS. and Griffin JB. (2019) A retrospective cohort study of safety outcomes in New Zealand infants exposed to tdap vaccine in utero. Vaccines 7(4) http://dx.doi.org/10.3390/vaccines7040147. (Journal Articles)
  • Griffin JB., Yu L., Watson D., Turner N., Walls T., Howe AS., Jiang Y. and Petousis-Harris H. (2018) Pertussis Immunisation in Pregnancy Safety (PIPS) Study: A retrospective cohort study of safety outcomes in pregnant women vaccinated with Tdap vaccine. Vaccine 36(34): 5173-5179. http://dx.doi.org/10.1016/j.vaccine.2018.07.011. (Journal Articles)
  • Lawton B., Howe AS., Turner N., Filoche S., Slatter T., Devenish C. and Hung NA. (2018) Association of prior HPV vaccination with reduced preterm birth: A population based study. Vaccine 36(1): 134-140. http://dx.doi.org/10.1016/j.vaccine.2017.11.020. (Journal Articles)
  • Howe AS., Heath ALM., Lawrence J., Galland BC., Gray AR., Taylor BJ., Sayers R. and Taylor RW. (2017) Parenting style and family type, but not child temperament, are associated with television viewing time in children at two years of age. PLoS ONE 12(12) http://dx.doi.org/10.1371/journal.pone.0188558. (Journal Articles)
  • Wong JE., Haszard JJ., Howe AS., Parnell WR. and Skidmore PML. (2017) Development of a healthy dietary habits index for New Zealand adults. Nutrients 9(5) http://dx.doi.org/10.3390/nu9050454. (Journal Articles)
  • Howe AS., Skidmore PML., Parnell WR., Wong JE., Lubransky AC. and Black KE. (2016) Cardiorespiratory fitness is positively associated with a healthy dietary pattern in New Zealand adolescents. Public Health Nutrition 19(7): 1279-1287. http://dx.doi.org/10.1017/S1368980015002566. (Journal Articles)
  • Mallard SR., Howe AS. and Houghton LA. (2016) Vitamin D status and weight loss: A systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials. American Journal of Clinical Nutrition 104(4): 1151-1159. http://dx.doi.org/10.3945/ajcn.116.136879. (Journal Articles)
  • Wong JE., Parnell WR., Howe AS., Lubransky AC., Black KE. and Skidmore PML. (2015) Diet quality is associated with measures of body fat in adolescents from Otago, New Zealand. Public Health Nutrition 18(8): 1453-1460. http://dx.doi.org/10.1017/S1368980014001645. (Journal Articles)
  • Cosgrove SD., Love TD., Brown RC., Baker DF., Howe AS. and Black KE. (2014) Fluid and electrolyte balance during two different preseason training sessions in elite rugby union players. Journal of Strength and Conditioning Research 28(2): 520-527. http://dx.doi.org/10.1519/JSC.0b013e3182986d43. (Journal Articles)
  • Gentle HL., Love TD., Howe AS. and Black KE. (2014) A randomised trial of pre-exercise meal composition on performance and muscle damage in well-trained basketball players. Journal of the International Society of Sports Nutrition 11(1) http://dx.doi.org/10.1186/1550-2783-11-33. (Journal Articles)
  • Howe AS., Mandic S., Parnell WR. and Skidmore PM. (2014) Attitudes to food differ between adolescent dieters and non-dieters from Otago, New Zealand, but overall food intake does not. Public Health Nutrition 16(1): 36-45. http://dx.doi.org/10.1017/S1368980012001152. (Journal Articles)
  • Howe AS., Black KE., Wong JE., Parnell WR. and Skidmore PM. (2013) Dieting status influences associations between dietary patterns and body composition in adolescents: A cross-sectional study. Nutrition Journal 12(1) http://dx.doi.org/10.1186/1475-2891-12-51. (Journal Articles)
  • Skidmore PM., Howe AS., Polak MA., Wong JE., Lubransky A., Williams SM. and Black KE. (2013) Sleep duration and adiposity in older adolescents from Otago, New Zealand: Relationships differ between boys and girls and are independent of food choice. Nutrition Journal 12(1) http://dx.doi.org/10.1186/1475-2891-12-128. (Journal Articles)
  • Wong JE., Parnell WR., Howe AS., Black KE. and Skidmore PML. (2013) Development and validation of a food-based diet quality index for New Zealand adolescents. BMC Public Health 13(1) http://dx.doi.org/10.1186/1471-2458-13-562. (Journal Articles)

Future Research

  • Targeted funding of Meningococcal Vaccines
  • Impact of Pnuemococcal Vaccines on Anti-infective Prescribing
  • Use of anti-nausea drugs during pregnancy and child outcomes
  • Fatness and vaccine effectiveness
  • Maternal immunisation coverage

Key Methodologies

  • Quantitative methods
  • Cohort studies
  • Administrative Data
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