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    • Research at UC

Dr Timothy Bryan Franci Woodfield

Contact

Department: Mechanical Engineering

Email: tim.woodfield@canterbury.ac.nz

Office:

Language: English

About
Research / Creative works
Networks

Fields of Research

  • Biodegradable porous scaffolds
  • Biomaterials
  • Bone tissue engineering
  • Cartilage tissue engineering
  • Rapid prototyping of biomaterials
  • Replacing damaged tissue with patients own cells
  • Skin tissue engineering
  • Stem cells
  • Tissue Engineering
  • Total joint arthroplasty

Researcher Summary

Research interests include:
- Scaffold/biomaterial design for functional tissue-engineered implants: cell-biomaterial interactions; articular cartilage, bone, neural/nerve tissue engineering; smart/instructive biomaterials (i.e. inductive materials/architectures, growth factor/drug release, cell free solutions); engineered porous scaffold architectures (topology optimisation); anisotropic/biphasic scaffold design; biodegradation and mechanical function with respect to tissue integration; in vitro/in vivo models using committed, progenitor and stem cells.
- Solid Free-from Fabrication (SFF) of porous biomaterials: engineered porous scaffold architectures; development of SFF “friendly” biomaterials; SFF of porous polymeric, Ti/Ti-alloys, and ceramic biomaterials; electro-spinning; bone in-growth surfaces; bio-manufacturing/cell printing; clinical applications for customised implants/joint reconstruction.
- Mechanobiology of cells/connective tissues: measurement/optimisation of nutrient gradients (e.g. oxygen, glucose) and their subsequent effects on tissue formation; cellular responses to mechanical stimuli; computational/in vitro models; bioreactor design.
- Orthopaedic applications: total joint arthroplasty; proprioceptive ability of patients following TKA; wheelchair propulsion ability in SCI subjects; spinal fusion devices; biodegradable conduits for nerve/spinal cord regeneration; cell therapy/tissue engineering applications in regenerative medicine.

Subject Area: Disciplines

  • Engineering and Technology: Bioengineering

Research/Scholarly/Creative Works

  • Mutreja I., Woodfield T., Sperling S., Nock V., Evans JJ. and Alkaisi MM. (2015) Positive and negative bioimprinted polymeric substrates: new platforms for cell culture. Biofabrication 7(2) 25002: 13pp. http://dx.doi.org/10.1088/1758-5090/7/2/025002. (Journal Articles)
  • Mutreja I., Sperling S., Nock V., Alkaisi MM. and Woodfield TBF. (2014) Fabrication of Bioimprinted polymeric substrates with micro- and nano-scale topography: new platforms for cell culture. Pohang, South Korea: International Conference on Biofabrication 2014, 28 Sep-1 Oct 2014. (Conference Contributions - Other)
  • Rajendran K., Walsh MF., de Ruiter NJA., Chernoglazov AI., Panta RK., Butler APH., Butler PH., Bell ST., Anderson NG. and Woodfield TBF. (2014) Reducing beam hardening effects and metal artefacts using Medipix3RX: With applications from biomaterial science. Journal of Instrumentation 9: 1-11. http://dx.doi.org/10.1088/1748-0221/9/03/P03015. (Journal Articles)
  • Khan-Edmundson A., Rodgers GW., Woodfield TBF., Hooper GJ. and Chase JG. (2012) Tissue attenuation characteristics of acoustic emission signals for wear and degradation of total hip arthoplasty implants. In Biological and Medical Systems 8(1): 355-360. http://dx.doi.org/10.3182/20120829-3-HU-2029.00046. (Conference Contributions - Published)
  • Lang M., Chen XQ., Wang WH. and Woodfield T. (2012) Injection system for cellular assembly of 3D bio-tissue engineered constructs. In : 287-292. http://dx.doi.org/10.1109/CoASE.2012.6386394. (Conference Contributions - Published)
  • Murray LM., Nock V., Alkaisi MM., Lee JJM. and Woodfield TBF. (2012) Fabrication of polymeric substrates with micro- and nanoscale topography bioimprinted at progressive cell morphologies. Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures: Processing, Measurement, and Phenomena 30 06F902 http://dx.doi.org/10.1116/1.4758759. (Journal Articles)
  • Kirkland NT., Kolbeinsson I., Dias GJ., Woodfield T. and Staiger MP. (2011) Synthesis and properties of topologically-ordered porous magnesium. Materials Science and Engineering B 176(20): 1666-1672. http://dx.doi.org/10.1016/j.mseb.2011.04.006. (Journal Articles)
  • Nguyen T., Staiger MP., Dias G. and Woodfield T. (2011) Relationship between surface roughness and corrosion rate of pure magnesium biomaterials. In. (Conference Contributions - Published)
  • Nguyen TL., Staiger MP., Dias GJ. and Woodfield TBF. (2011) A novel manufacturing route for fabrication of topologically-ordered porous magnesium scaffolds. Advanced Engineering Materials 13(9): 872-881. http://dx.doi.org/10.1002/adem.201100029. (Journal Articles)
  • Shadanbaz S., Pietak A., Staiger MP., Woodfield T. and Dias GJ. (2011) In situ crystallisation - a novel calcium phosphate coating technique on pure magnesium: in vitro corrosion protection analysis. In. (Conference Contributions - Published)
  • Walker J., Staiger MP., Woodfield T. and Dias G. (2011) The development of an intermuscular model to investigate the biocompatibility of magnesium alloys. In. (Conference Contributions - Published)
  • Waterman J., Kirkland N., Hartshorn R., Birbilis N., Woodfield T., Dias G. and Staiger MP. (2011) NMR studies on the complex behaviour of magnesium and HEPES for in vitro testing. In. (Conference Contributions - Published)
  • Waterman J., Pietak A., Birbilis N., Woodfield T., Dias G. and Staiger MP. (2011) Corrosion resistance of biomimetic calcium phosphate coatings on magnesium due to varying pretreatment time. Materials Science and Engineering B 176(20): 1756-1760. http://dx.doi.org/10.1016/j.mseb.2011.06.021. (Journal Articles)
  • Kirkland NT., Birbilis N., Walker J., Woodfield T., Dias GJ. and Staiger MP. (2010) In-vitro dissolution of magnesium-calcium binary alloys: Clarifying the unique role of calcium additions in bioresorbable magnesium implant alloys. Journal of Biomedical Materials Research Part B: Applied Biomaterials 95B(1): 91-100. http://dx.doi.org/10.1002/jbm.b.31687. (Journal Articles)
  • Lang M., Wang WH., Chen XQ. and Woodfield T. (2010) Automated 3D scaffold printing and seeding. In : 786-791. (Conference Contributions - Published)
  • Woodfield TBF., Lang M., Wang WH. and Chen XQ. (2010) System and method for 3D tissue assembly.Patent No. NZ587478. (Intellectual Property)
  • Dalton PD., Woodfield T. and Hutmacher DW. (2009) Snapshot: Polymer scaffolds for tissue engineering. Biomaterials 30(4): 701-702. http://dx.doi.org/10.1016/S0142-9612(08)00900-9. (Journal Articles)
  • Kirkland NT., Kolbeinsson I., Woodfield T., Dias G. and Staiger MP. (2009) Processing-Property Relationships of As-Cast Magnesium Forms With Controllable Architecture. International Journal of Modern Physics B 23(6-7): 1002-1008. http://dx.doi.org/10.1142/S0217979209060373. (Journal Articles)
  • Kirkland NT., Staiger MP., Walker J., Dias G. and Woodfield TBF. (2009) Biocompatibility screening methods for magnesium alloys in orthopaedic applications. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Nguyen T., Staiger MP., Rabczuk T., Dias G. and Woodfield TBF. (2009) Topology optimisation and finite element analysis of ordered porous bone interfacing implants. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Spitters T., Stroebel S., Malda J. and Woodfield TBF. (2009) Perfusion seeding of chondrocytes into 3D-printed polymer scaffolds. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Staiger MP., Kirkland NT., Kolbeinsson I., Walker J., Dias G. and Woodfield TBF. (2009) A Manufacturing Route For Cellular Magnesium With Ordered Architecture Aimed At Orthopaedic Applications. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Stroebel S., Woodfield TBF., Wendt D., Krause C. and Martin I. (2009) Physiological Oxygen Levels Can Enhance The Chondrogenic Redifferentiation Of Human Chondrocytes In 3D Constructs Cultured Under Perfusion. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Walker J., Kirkland J., Staiger MP., Woodfield TBF. and Dias G. (2009) HET-CAM: A rapid and inexpensive screening technique for the inflammatory potential of biomaterials. University of New South Wales, Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Waterman J., Staiger MP., Pietak A., Mahoney T., Dias GJ. and Woodfield TBF. (2009) Biomimetic calcium phosphate coatings for improved magnesium metal based orthopaedic implants. Sydney, Australia: 19th Annual Conference of the Australasian Society for Biomaterials and Tissue Engineering (ASBTE), 21-23 Jan 2009. (Conference Contributions - Other)
  • Woodfield TBF., Guggenheim M., von Rechenberg B., Riesle J., van Blitterswijk CA. and Wedler V. (2009) Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints. Cell Proliferation 42(4): 485-497. http://dx.doi.org/10.1111/j.1365-2184.2009.00608.x. (Journal Articles)
  • Woodfield TBF., Moroni L. and Malda J. (2009) Combinatorial Approaches to Controlling Cell Behaviour and Tissue Formation in 3D via Rapid-Prototyping and Smart Scaffold Design. Combinatorial Chemistry & High Throughput Screening 12(6): 562-579. (Journal Articles)
  • Gooch SD., Woodfield TBF., Hollingsworth L., Rothwell AG., Medland AJ. and Yao F. (2008) On the Design of Manual Wheelchairs for People with Spinal Cord Injuries. In Proceedings of the DESIGN 2008: 387-394. (Conference Contributions - Published)
  • Hutmacher D., Woodfield T., Dalton P. and Lewis J. (2008) Scaffold design and fabrication. In van Blitterswijk CA; Thomsen P; Hubbell J; Cancedda R; de Bruijn JD; Lindahl A; Sohier J; Williams DF (Ed.), Tissue Engineering: 403-454. London: Academic Press. (Chapters)
  • Kirkland NT., Kolbeinsson I., Woodfield T., Dias G. and Staiger MP. (2008) Processing-property relationships of as-cast magnesium foams with controllable architecture. Harbin, China: 5th International Conference on Advanced Materials and Processing (ICAMP-5), 2-5 Sep 2008. (Conference Contributions - Other)
  • Kolbeinsson I., Staiger MP., Dias G. and Woodfield TBF. (2008) A Novel Processing Route for the Manufacture of Salt Templates With A Controlled Porous Structure. Harbin, China: 5th International Conference on Advanced Materials and Processing (ICAMP-5), 2-5 Sep 2008. (Conference Contributions - Other)
  • Malda J., Radisic M., Levenberg S., Woodfield T., Oomens C., Baaijens F., Svalander P. and Vunjak-Novakovic G. (2008) Cell nutrition. In van Blitterswijk CA; Thomsen P; Hubbell J; Cancedda R; de Bruijn JD; Lindahl A; Sohier J; Williams DF (Ed.), Tissue Engineering: 327-362. London: Elsevier. (Chapters)
  • Woodfield TBF., Hooper G., Vincent A. and Bell V. (2008) Evaluation of Knee Joint Proprioception Following Anterior Cruciate Ligament Reconstruction - a 1-year follow-up. Hastings, New Zealand: New Zealand Orthopaedic Association (NZOA) Annual Scientific Meeting 2008, 19-22 Oct 2008. (Conference Contributions - Other)
  • Gooch S., Rothwell A., Yao F., Dunn J. and Woodfield T. (2007) A Procedure for Measuring Manual Wheelchair Propulsion Ability for People with Spinal Cord Injuries. Shriners Hospitals for Children, Philadelphia, PA, USA: International Meeting on Upper Limb in Tetraplegia Conference, 17-20 Sep 2007. (Conference Contributions - Other)
  • Gooch S., Rothwell A., Yao F., Dunn J. and Woodfield T. (2007) Quantifying Manual Wheelchair Propulsion Ability vs. Injury Level for People with Spinal Cord Injuries. Shriners Hospitals for Children, Philadelphia, PA, USA: International Meeting on Upper Limb in Tetraplegia Conference, 17-20 Sep 2007. (Conference Contributions - Other)
  • Hollingsworth L., Medland A., Gooch S., Rothwell A., Lintott A. and Woodfield T. (2007) Using Constraint Modelling to Predict the Upper Body Strength Capabilities of People with Tetraplegia. Shriners Hospitals for Children, Philadelphia, PA, USA: International Meeting on Upper Limb in Tetraplegia Conference, 17-20 Sep 2007. (Conference Contributions - Other)
  • Woodfield T., de Vries H., Hooper G. and Rothwell A. (2007) Cartilage Tissue Engineering Using Smart Scaffold Design & Advanced Bio-manufacturing. Auckland, New Zealand: New Zealand Orthopaedic Association (NZOA) Annual Scientific Meeting, 14-17 Oct 2007. (Conference Contributions - Other)
  • Woodfield T., Moroni L., Wilson CE. and van Blitterswijk CA. (2007) Smart Scaffold Design and Bio-manufacturing in Regenerative Medicine. Melbourne, Australia: Australasian Society for Biomaterials 17th Annual Conference, 11-13 Apr 2007. (Conference Contributions - Other)
  • Woodfield T., van Vlimmeren M. and Mackay-Sim A. (2007) Solid Free-form Fabrication of nerve guide conduits for developing a 3D in vitro neurogenesis model. London, UK: Tissue Engineering & Regenerative Medicine International Society European Chapter (TERMIS-EU) Conference, 4-7 Sep 2007. (Conference Contributions - Other)
  • Habibovic P., Woodfield T., de Groot K. and van Blitterswijk C. (2006) Predictive Value of In Vitro Assays in Research of Bone and Cartilage Regeneration: What do They Really Tell Us About the Clinical Performance? Advances in Experimental Medicine & Biology 585(1): 327-360. (Journal Articles)
  • Woodfield T. (2006) Solid Free-Form Fabrication of Tissue Engineered Constructs. National University of Singapore, Singapore: 3rd International Symposium on Biomodeling & Bioprinting, 09 Jun 2006. (Oral Presentations)
  • Woodfield T. (2006) Biological Scaffolds in Tissue Engineering & Regenerative Medicine. Christchurch, New Zealand: 5th Asia Pacific Orthopaedic Society for Sports Medicine (APOSSM) Congress, 1-1 Aug 2006. (Conference Contributions - Other)
  • Woodfield TBF., Miot S., Martin I., van Blitterswijk CA. and Riesle J. (2006) The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification. Biomaterials 27(7): 1043-1053. (Journal Articles)
  • Malda J., Woodfield TBF., van der Vloot F., Wilson C., Martens DE., Tramper J., van Blitterswijk CA. and Riesle J. (2005) The Effect of PEGT/PBT Scaffold Architecture on the Composition of Tissue Engineered Cartilage. Biomaterials 26(1): 63-72. (Journal Articles)
  • Miot S., Woodfield T., Daniels AU., Suetterlin R., Peterschmitt I., Heberer M., van Blitterswijk CA., Riesle J. and Martin I. (2005) Effects of Scaffold Composition and Architecture on Human Nasal Chondrocyte Redifferentiation and Cartilagenous Matrix Deposition. Biomaterials 26(15): 2479-2489. (Journal Articles)
  • Woodfield T., Malda J., Miot S., Martin I., van Blitterswijk CA. and Riesle J. (2005) Optimized Scaffolds for Optimized Tissues: Scaffold Composition and 3D Architecture Synergistically Enhance Cell Redifferentiation and Tissue Formation. Munich, Germany: SocEuropean Tissue Engineeringiety (ETES) / International Cartilage Repair Society (ICRS) 4th Annual Meeting, 31 Aug 2005. (Conference Contributions - Other)
  • Woodfield T., Miot S., Martin I., van Blitterswijk CA. and Riesle J. (2005) Cell-Based Tissue Engineering Approaches to Repairing Articular Cartilage: Optimised Scaffolds for Optimised Tissues. Christchurch, New Zealand: New Zealand Orthopaedic Assoc (NZOA) Annual Scientific Meeting, 2 Oct 2005. (Conference Contributions - Other)
  • Woodfield TBF., van Blitterswijk CA., de Wijn J., Sims TJ., Hollander AP. and Riesle J. (2005) Polymer Scaffolds Fabricated with Pore-Size Gradients as a Model for Studying the Zonal Organization within Tissue-Engineered Cartilage Constructs. Tissue Engineering 11(9-10): 1297-1311. (Journal Articles)
  • Malda J., Woodfield TBF., van der Vloodt F., Kooya FK., Martens DE., Tramper J., van Blitterswijk CA. and Riesle J. (2004) The Effect of PEGT/PBT Scaffold Architecture on Oxygen Gradients in Tissue Engineered Cartilaginous Constructs. Biomaterials 25(26): 5773-5780. (Journal Articles)
  • Woodfield T., de Wijn J., Sims T., Hollander A., van Blitterswijk CA. and Riesle J. (2004) Polymer Scaffolds Fabricated with Organised Pore-size Gradient Structures as a Model for Studying the Zonal Organisation within Tissue Engineered Cartilage Constructs. Sydney, Australia: 7th World Biomaterials Congress, 17 May 2004. (Conference Contributions - Other)
  • Woodfield T., Miot S., Martin I., van Blitterswijk CA. and Riesle J. (2004) Gas Plasma Treatment and PEGT/PBT Substrate Composition Regulate Human Chondrocyte Adhesion and Re-differentiation Capacity. Sydney, Australia: 7th World Biomaterials Congress, 17 May 2004. (Conference Contributions - Other)
  • Woodfield T., Miot S., van Blitterswijk CA., Riesle J. and Martin I. (2004) Human Chondrocyte Re-differentiation and Cartilaginous Matrix Deposition are Controlled by 3D Scaffold Composition and Architecture. Sydney, Australia: 7th World Biomaterials Congress, 17 May 2004. (Conference Contributions - Other)
  • Woodfield T., Wedler V., Schneller M., Riesle J. and van Blitterswijk CA. (2004) Towards Customised Tissue Engineered Implants for Reconstruction of Small Articular Joints. Sydney, Australia: 7th World Biomaterials Congress, 17 May 2004. (Conference Contributions - Other)
  • Woodfield TBF. (2004) Cartilage Tissue Engineering: instructing cell-based tissue repair through scaffold design. Enschede, The Netherlands. University of Twente / IsoTis S.A. (Theses / Dissertations)
  • Woodfield TBF., Malda J., de Wijn J., Péters F., Riesle J. and van Blitterswijk CA. (2004) Design of Porous Scaffolds for Cartilage Tissue Engineering Using a Three-Dimensional Fibre-Deposition Technique. Biomaterials 25(18): 4149-4161. (Journal Articles)
  • Woodfield T., Wedler V., Schneller M., van Blitterswijk CA. and Riesle J. (2003) Rapid Prototyped Scaffolds for the Resurfacing of Small Articular Joints. Genova, Italy: European Tissue Engineering Society (ETES) / International Cartilage Repair Society (ICRS) Meeting, 21 Sep 2003. (Conference Contributions - Other)
  • Woodfield T., Mahmood T., Riesle J. and van Blitterswijk CA. (2002) Enhanced Cell Attachment and Onset of Chondrogenesis on Glow Discharge Treated 2D and 3D PEGT/PBT Scaffolds. Dallas, TX, USA: 48th Annual Meeting of the Orthopaedic Research Society, 10 Feb 2002. (Conference Contributions - Other)
  • Woodfield T., Malda J., de Wijn J., Riesle J. and van Blitterswijk CA. (2002) Fabrication of PEGT/PBT Scaffolds Containing an Organized Pore-size Gradient Structure. Toronto, Canada: 4th International Cartilage Repair Society (ICRS) Symposium, 15 Jun 2002. (Conference Contributions - Other)
  • Woodfield T., Malda J., de Wijn J., Riesle J. and van Blitterswijk CA. (2002) PEGT/PBT Scaffolds Fabricated with Organized Pore-size Gradient Structures for Cartilage Tissue Engineering Applications. Barcelona, Spain: European Society for Biomaterials (ESB) Conference, 11 Sep 2002. (Conference Contributions - Other)
  • Woodfield T., Malda J., de Wijn J., Riesle J. and van Blitterswijk CA. (2002) Polymer Scaffolds Fabricated with Organized Pore-size Gradient Structures for Cartilage Tissue Engineering. Lunteren, The Netherlands: Nederlandse Vereniging voor Biomaterialen (NVB, Dutch Biomaterials Society) Conference, 1 Dec 2002. (Conference Contributions - Other)
  • Woodfield T., Malda J., de Wijn J., Riesle J. and van Blitterswijk CA. (2002) Porous PEGT/PBT Scaffolds for Cartilage Tissue Engineering Fabricated Using a 3D-Deposition Technique. Frieburg, Germany: Workshop on Rapid Prototyping for Biomedical Applications, 1 May 2002. (Conference Contributions - Other)
  • Woodfield TBF., Bezemer JM., Pieper JS., van Blitterswijk CA. and Riesle J. (2002) Scaffolds for Tissue Engineering of Cartilage. Critical Reviews in Eukaryotic Gene Expression 12(3): 209-236. (Journal Articles)
  • Woodfield T., de Wijn J., Riesle J. and van Blitterswijk CA. (2001) In Vitro Cartilage Tissue Formation on Porous PEGT/PBT Scaffolds Fabricated Using a 3D-Deposition Technique. Frieburg, Germany: European Tissue Engineering Society (ETES) / International Cartilage Repair Society (ICRS) Meeting, 7 Nov 2001. (Conference Contributions - Other)
  • Woodfield T., de Wijn J., Riesle J. and van Blitterswijk CA. (2001) Porous PEGT/PBT Scaffolds for Cartilage Tissue Engineering Fabricated Using a 3D-Deposition Technique - A Preliminary Evaluation. London, UK: European Society for Biomaterials (ESB) Conference, 12 Sep 2001. (Conference Contributions - Other)
  • Woodfield T., de Wijn J., Haan R., Riesle J. and van Blitterswijk CA. (2000) Mechanical Evaluation of Porous PEGT/PBT scaffolds for Tissue Engineering of Articular Cartilage. Lunteren, The Netherlands: Nederlandse Vereniging voor Biomaterialen (NVB, Dutch Biomaterials Society) Conference, 1 Dec 2000. (Conference Contributions - Other)

Affiliations

  • University of Otago, Christchurch School of Medicine & Health Sciences (Teaching/Research Organisation): Clinical Lecturer, Department of Orthopaedic Surgery & Musculoskeletal Medicine
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