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Associate Professor Paul T Gaynor

Contact

Department: Electrical and Computer Engineering

Email: paul.gaynor@canterbury.ac.nz

Phone Number: +64 3 369 3999 ext. null

Office: Link Rm 506

Language: English

About
Research / Creative works
Networks
Projects

Fields of Research

  • Biological applications of electric fields
  • Electroporation and dielectrophoresis applications
  • Bio-instrumentation for swallowing rehabilitation
  • High voltage analogue electronics
  • Low environmental impact electric power generation
  • Electric Vehicle Development

Researcher Summary

Research interests include:
-Electric field biomedical treatments: research focuses on applications of electroporation and dielectrophoreisis. Electroporation is a term that is used for the observed increase in permeability of biological membranes to macromolecules through application of high magnitude electric field pulses. The increased membrane permeability allows the transport of material across the membrane that would otherwise be blocked. This effect has significant applications in research including genetic engineering, gene therapy, cancer chemotherapy and cloning. Dielectrophoresis is defined as medium magnitude AC non-linear electric field induced movement of cells. The movement can be used to separate mixed cell types, transport cells from place to place, and arrange cells into structures. This effect has applications in disease diagnosis, immunology, cell characterisation, and cloning.
-Power electronics applications: research is primarily involved with the design and construction of high voltage power electronics. Of particular interest are high voltage electronics associated with electroporation research, and small-scale electrical power generation using sustainable energy sources.
-Electro-biotechnology: Bio-feedback rehabilitation devices, electrostatic allergen control, electro-surgery, and neural stimulation.

Subject Area: Disciplines

  • Agriculture and Other Applied Biological Sciences: Biotechnology
  • Engineering and Technology: Electrical Engineering; Power Systems & Power Electronics; Resource/Environment Engineering

Resources

  • Staff webpage

Research/Scholarly/Creative Works

Journal Articles
  • Omar A., Wood A., Laird H. and Gaynor P. (2022) Single-Phase Charging of EV Embedded Batteries in an MMC with Submodule Override Capability. Energies 15(6) http://dx.doi.org/10.3390/en15062276.
  • Cronje T. and Gaynor PT. (2019) Electroporation of Ishikawa cells: analysis by flow cytometry. IET Nanobiotechnology 13(1): 58-65. http://dx.doi.org/10.1049/iet-nbt.2018.5194.
  • Benhal P., Chase JG., Gaynor P., Oback B. and Wang WH. (2015) Multiple-cylindrical Electrode System for Rotational Electric Field Generation in Particle Rotation Applications. International Journal of Advanced Robotic Systems 12(84): 12pp-12pp. http://dx.doi.org/10.5772/60456.
  • Benhal P., Chase JG., Gaynor P., Oback B. and Wang W. (2014) AC electric field induced dipole-based on-chip 3D cell rotation. Lab on a Chip 14(15): 2717-2727. http://dx.doi.org/10.1039/c4lc00312h.
  • Chester CJ., Gaynor PT., Jones RD. and Huckabee M-L. (2014) Electrical bioimpedance measurement as a tool for dysphagia visualisation. Healthc Technol Lett 1(3): 115-118. http://dx.doi.org/10.1049/htl.2014.0067.
  • Shillington R., Gaynor P., Harrison M. and Heffernan W. (2012) Silicon carbide JFET reverse conduction characteristics and use in power converters. IET Power Electronics 5(8): 1282-1290. http://dx.doi.org/10.1049/iet-pel.2011.0404.
  • Clow AL., Gaynor PT. and Oback BJ. (2010) A novel micropit device integrates automated cell positioning by dielectrophoresis and nuclear transfer by electrofusion. Biomedical Microdevices 12(5): 777-786. http://dx.doi.org/10.1007/s10544-010-9432-3.
  • Talele S., Gaynor P., Cree MJ. and Van Ekeran J. (2010) Modelling single cell electroporation with bipolar pulse parameters and dynamic pore radii. Journal of Electrostatics 68(3): 261-274. http://dx.doi.org/10.1016/j.elstat.2010.02.001.
  • Clow A., Gaynor P. and Oback B. (2009) Coplanar film electrodes facilitate bovine nuclear transfer cloning. Biomedical Microdevices 11(4): 851-859. http://dx.doi.org/10.1007/s10544-009-9302-z.
  • Talele S. and Gaynor P. (2008) Non-linear time domain model of electropermeabilization: Effect of extracellular conductivity and applied electric field parameters. Journal of Electrostatics 66(5-6): 328-334. http://dx.doi.org/10.1016/j.elstat.2008.02.002.
  • Talele S. and Gaynor P. (2007) Non-linear time domain model of electropermeabilization: Response of a single cell to an arbitrary applied electric field. Journal of Electrostatics 65(12): 775-784. http://dx.doi.org/10.1016/j.elstat.2007.06.004.
  • Gaynor PT. and Bodger PS. (2006) Physical modelling of electroporation in close cell-to-cell proximity environments. Physics in Medicine and Biology 51(12): 3175-3188. http://dx.doi.org/10.1088/0031-9155/51/12/012.
  • Gaynor P., Wells DN. and Oback B. (2005) Couplet alignment and improved electrofusion by dielectrophoresis for a zona-free high-throughput cloned embryo production system. Medical and Biological Engineering and Computing 43(1): 150-154. http://dx.doi.org/10.1007/BF02345137.
  • Hurd SA., Carnegie DA., Brown NR. and Gaynor PT. (2005) Development of an intelligent robotic system for the automation of a meat-processing task. International Journal of Intelligent Systems Technologies and Applications 1(1/2): 32-48. http://dx.doi.org/10.1504/IJISTA.2005.007306.
  • Hurd SA., Carnegie DA., Brown NR. and Gaynor PT. (2005) Development of an intelligent robotic system for the automation of a meat-processing task. International Journal of Intelligent Systems Technologies and Applications 1(1-2): 32-48. http://dx.doi.org/10.1504/ijista.2005.007306.
  • Oback B., Wiersma AT., Gaynor P., Laible G., Tucker FC., Oliver JE., Miller AL., Troskie HE., Wilson KL. and Forsyth JT. (2003) Cloned Cattle Derived from a Novel Zona-Free Embryo Reconstruction System. Cloning and Stem Cells 5(1): 3-12.
  • Hughes JF., Gaunt LF. and Gaynor PT. (2002) Electrostatic targeting for allergen removal and pest control applications. Journal of Electrostatics 55(3-4): 237-245.
  • Gaynor PT. and Hughes JF. (1998) Dust anchoring characteristics of electret fibres with respect to Der p 1 allergen carrying particles. Medical and Biological Engineering and Computing 36(5): 615-620. http://dx.doi.org/10.1007/BF02524433.
  • Gaynor PT. and Hughes JF. (1998) Dust anchoring characteristics of electret fibres with respect to Der p 1 allergen. Medical & Biological Engineering & Computing 36: 615-620.
  • Gaynor PT. and Hughes JF. (1998) Electrostatic charge characteristics of Der p 1 allergen carrying particles and house dust mite, Dermatophagoides pteronyssinus. Medical & Biological Engineering & Computing 36: 351-354.
  • Elder PA., Gaynor PT., Lewis JG., Bodger PS. and Bason LM. (1997) Generation of monoclonal progesterone antibodies by electrofusion techniques. Bioelectrochemistry and Bioenergetics 43: 35-40.
  • Elder PA., Gaynor PT., Lewis JG., Bodger PS. and Bason LM. (1997) Generation of monoclonal progesteroneantibodies by electrofusion techniques. Bioelectrochemistry and Bioenergetics - February 1997 43: 35-40.
  • Gaynor PT. and Bodger PS. (1995) Balloon model of biological cell electropermeabilization in relation to the radius dependence of membrane dielectric breakdown. IEE Proceedings on Science Measurement and Technology 142: 277-282.
  • Gaynor PT. and Bodger PS. (1995) Electrofusion processes: theoretical evaluation of high electric field effects on cellular transmembrane potentials. IEE Proceedings on Science, Measurement and Technology 142: 176-182.
  • Gaynor PT. and Bodger PS. (1994) Ionisation of dielectric spheroid membranes: a balloon model of electroporation of biological cells. IEE Proceedings on Science Measurement and Technology 141: 190-196.
Chapters
  • Talele S. and Gaynor PT. (2010) Modelling control of pore number and Radii distribution in single-cell electroporation. In Elleithy K; Sobh T; Iskander M; Kapila V; Karim MA; Mahmood A (Ed.), Research Publications in Technological Developments in Networking, Education and Automation: 231-236. New York: Springer. http://dx.doi.org/10.1007/978-90-481-9151-2.
  • Talele S., Gaynor PT., Van Ekeran J. and Cree M. (2010) Modelling Single Cell Electroporation with Bipolar Pulse: Simulating Dependance of Electroporated Fractional Pore Area on the Bipolar Field Frequency. In Iskander M; Kapila V; Karim MA; Mahmood A (Ed.), Technological Developments in Education and Automation: 355-359. New York: Springer. http://dx.doi.org/10.1007/978-90-481-3656-8_65.
Conference Contributions - Published
  • Omar A., Wood A., Laird H. and Gaynor P. (2021) Simplified SOC Balancing of an MMC with Embedded Storage in an EV System. In IEEE Region 10 Annual International Conference, Proceedings/TENCON 2021-December: 929-934. http://dx.doi.org/10.1109/TENCON54134.2021.9707466.
  • Wei J., Gaynor P., Cole S., Brophy B., Oback B. and Laible G. (2018) Developing the condition for bovine zygote-mediated genome editing by electroporation. In Proceedings of the World Congress on Genetics Applied to Livestock Production Technologies - Gene Editing: 1118-1122.
  • Lippitt A., Gaynor P., Jones RD. and Huckabee M-L. (2015) The development of an impedance-based swallowing biofeedback device. (Abstract). In Australasian Physical & Engineering Sciences in Medicine 38: 186-186.
  • Cronje T. and Gaynor P. (2013) High Voltage and Frequency Bipolar Pulse Generator Design for Electroporation-based Cancer Therapy. In : 7pp.
  • Chen XQ., Chase JG., Wang W., Gaynor P. and McInnes AI. (2010) Embedding Design Projects into Multidisciplinary Engineering Education. In http://dx.doi.org/10.1109/ICEIT.2010.5608345.
  • Cronje TF., Gaynor PT. and Lau G. (2010) A new multipurpose cancer zapper. In The New Zealand Medical Journal 123(1324): 96.
  • Gaynor PT., Webb RY. and Lloyd CC. (2010) Power Generation Using Low Temperature Differential Stirling Engine Technology. In.
  • Heffernan B., Duke R., Zhang R., Gaynor P. and Cusdin M. (2010) A Go-cart as an Electric Vehicle for Undergraduate Teaching and Assessment. In.
  • Shillington R., Gaynor P., Harrison M. and Heffernan B. (2010) Applications of Silicon Carbide JFETs in Power Converters. In.
  • Clow A., Gaynor P. and Oback B. (2009) A Micropit for Biological Cell Positioning. In : 837-841. http://dx.doi.org/10.1109/ICCA.2009.5410507.
  • Gaynor P., Webb R. and Lloyd C. (2009) Low Enthalpy Heat Stirling Engine Based Power Generation: A Research Design. In 2nd International Conference on Clean Electrical Power: 615-618. http://dx.doi.org/10.1109/ICCEP.2009.5211990.
  • Hasler MD., Gaynor P. and Carnegie D. (2009) Simulation for Improvement of Dynamic Path Planning Algorithms in Autonomous Search and Rescue Robots. In : 1603-1608. http://dx.doi.org/10.1109/ICCA.2009.5410391.
  • Talele S. and Gaynor P. (2009) Modelling Control of Pore Number and Radii Distribution in Single-Cell Electroporation. In.
  • Chen X., Gaynor P., King R., Chase G., Bones P., Gough P. and Duke R. (2008) A Project-Based Mechatronics Program to Reinforce Mechatronic Thinking - a Restructuring Experience from the University of Canterbury. In.
  • Chen X., Gaynor P., King R., Chase JG., Bones P., Gough P. and Duke R. (2008) A project-based mechatronics program to reinforce mechatronic thinking - A restructuring experience. In IFAC Proceedings Volumes (IFAC-PapersOnline) 17(1 PART 1) http://dx.doi.org/10.3182/20080706-5-KR-1001.0406.
  • Gaynor P., Webb R., Lloyd C. and Bodger PS. (2008) A Low Temperature Stirling Engine-based Power Generation Research Programme. In Proceedings of the Second IASTED Africa Conference: Power and Energy Systems (AfricaPES 2008)(Paper 602-061): 97-101.
  • Gaynor PT., Webb RY. and Lloyd CC. (2008) Low Temperature Differential Stirling Engine-Based Power Generation. In http://dx.doi.org/10.1109/ICSET.2008.4747058.
  • Clow LA., Künnemeyer R., Gaynor P. and Sharpe JC. (2007) Low cost optical particle detection for lab on chip systems based on DVD technology. In Proceedings of SPIE 6799(BioMEMS and Nanotechnology III): 67990S. http://dx.doi.org/10.1117/12.759283.
  • Cronje TF. and Gaynor PT. (2007) A New Multipurpose Cancer Zapper: The Way Forward. In Proceedings of the Fourteenth Electronics New Zealand Conference (ENZCon 2007): 89-94.
  • Hasler MD., Gaynor P. and Carnegie D. (2006) Dynamic Path Planning for Search and Rescue Robots. In Proceedings of the Thirteenth Electronics New Zealand Conference ENZCon'06: 99-102.
  • Howarth B., Gaynor P. and Carnegie D. (2006) Design of a medium sized wheeled robot for Urban Search and Rescue. In Proceedings of the Thirteenth Electronics New Zealand Conference ENZCon'06: 35-39.
  • Gaynor PT., Oback B. and Wells DN. (2003) Improved electrofusion procedure to generate zona-free cloned embryos by somatic nuclear transfer. In IFMBE Proceedings WC2003 4(CD-ROM).
  • Somerville A., Gaynor P. and Carnegie D. (2003) Predictive Analysis Software for Vehicles. In Proceedings of the 10th New Zealand Electronics Conference: 89-94.
  • Saad S. and Gaynor PT. (2001) Digital Signal Processing. In Proceedings of the Eighth New Zealand Electronics Conference: 137-140.
  • Skipwith JH. and Gaynor PT. (2001) High Voltage Linear Amplifier for Making Holey Cells. In Proceedings of the Eighth New Zealand Electronics Conference: 51-54.
  • Young P. and Gaynor PT. (2001) Piezoelectric Materials. In Proccedings of the Eighth New Zealand Electronics Conference: 69-72.
Conference Contributions - Other
  • Post S., Jermy M., Kabaliuk N., McNearney E. and Gaynor P. (2018) Real-time control of spray drop application. Montreal, Canada: 14th International Conference on Precision Agriculture, 24-27 Jun 2018.
  • Landon-Lane L., Miller A., Marshall A. and Gaynor P. (2017) Electrical Vehicle Storage Technologies and Range. Wellington: Electrical Engineering Association Conference 2017, 21-23 Jun 2017.
  • Acharya P. and Gaynor P. (2013) Direct Power Control Space Vector Modulation Technique Suitable for Turbines Operating at Variable Speeds. Kathmandu, Nepal: Fifth International Conference on Power and Energy Systems (ICPS), 28-30 Oct 2013.
  • Benhal P., Chase JG., Gaynor P. and Oback B. (2013) Simulation study of rotational electric field on spherical partical for electrorotation studies. Marina del Rey, CA, USA: 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013), 10-12 Apr 2013.
  • Benhal P., Chase JG., Gaynor P., Oback B. and Wang W. (2013) Dielectrophoresis Based 3D Cell Rotation through Integration Of Bottom And Vertical Electrodes. Freiburg, Germany: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013), 27-31 Oct 2013.
  • Benhal P., Chase JG., Gaynor P., Oback B. and Wang W. (2013) Vertical side wall electrode deposition for 3D cell rotation. Auckland, New Zealand: 6th International Conference on Advanced Materials and Technology (AMN6), 11-15 Feb 2013.
  • Benhal P., Chase JG., Wang WH., Gaynor P. and Oback B. (2013) A micro-device integrating vertical and bottom electrodes for 3D cell rotation. Auckland, New Zealand: 6th International Conference on Advanced Materials and Technology (AMN6), 11-15 Feb 2013.
  • Benhal P., Chase JG., Gaynor P., Oback B. and Wang W. (2012) Harmonic simulation study towards 3D cell rotation based on AC dielectrophoresis for biomedical applications. Wellington, New Zealand: 3rd Australia & New Zealand Micro/Nanofluidics and Bionano Symposium, 12-13 Apr 2012.
  • Clow A. and Gaynor P. (2007) Electrofusion of Asymmetrical Sized Biological Cells. Wellington, New Zealand: Third International Conference of Advanced Materials & Nanotechnology (AMN-3), 11-16 Feb 2007.
  • Talele S., Gaynor P., Van Ekeren J. and Cree M. (2007) Modelling membrane pore dynamics during electroporation of single spherical cell for bipolar field pulses. Kuala Lumpur, Malaysia: International Conference of Engineering Technology (ICET) 2007, 11-13 Dec 2007.
  • Talele S., Gaynor P., Van Ekeren J. and Cree M. (2007) Modelling membrane pore dynamics during electroporation of single spherical cell for multipulse electric field protocols. Coimbatore, India: International Conference On Modeling And Simulation (CITICOMS 2007), 27-29 Aug 2007.
  • Talele S. and Gaynor P. (2006) Nonlinear Time Domain Model Of Electropermeabilization: Response Of A Single Cell To An Arbitrary Applied Electric Field. New Delhi, India: 5th International Conference on Bioinformatics & Biotechnology (InCoB 2006), 18-20 Dec 2006.
  • McCormick JD., Carnegie DA., Gaynor PT. and Jensen C. (2004) A Switch Mode Power Supply for Audio Amplifiers. Palmerston North, New Zealand: 11th New Zealand Electronics Conference, 15 Nov 2004.
  • Jensen CH., Carnegie D. and Gaynor P. (2003) Universal Battery Powered Pulse Width Modulated H-Bridge Motor Control for Robotic Applications. Hamilton, New Zealand: 10th New Zealand Electronics Conference, 1 Sep 2003.
  • Gaynor PT. and Skipwith JH. (2002) A High Voltage Amplifier for use in Medical Applications of Electroporation. Christchurch, New Zealand: The First IEEE International Workshop on Electronic Design, Test and Applications.
  • Gaynor PT., Drake EJ. and Skipwith JH. (2002) A High Voltage Amplifier for use in Electropermeabilization Research. Rotorua, New Zealand: Engineering and Physical Sciences in Medicine Annual Conference, 10 Nov 2002.
  • Gaynor PT. and Geelen R. (1999) Reduction of cellular transmembrane potential variability in tissue electropermeabilization by ac electric field pulses. Surfers Paradise, Australia: Annual Conference on Engineering and the Physical Sciences in Medicine, 24 Oct 1999.
  • Gaynor PT. (1997) Electropermeabilization improvements relevant to in vivo applications. Nice, France: World Congress on Medical Physics and Biomedical Engineering, 14 Sep 1997.
  • Gaynor PT. and Hughes JF. (1997) House dust mite respirable allergen control by electrostatic anchoring on electret polymers. Nice, France: World Congress on Medical Physics and Biomedical Engineering, 14 Sep 1997.
  • Gaynor PT. and Hughes JF. (1997) Respirable particulate allergen control by electrostatic anchoring on electret polymers. Hobart, Australia: Annual Conference on Engineering and the Physical Sciences in Medicine, 15 Oct 2006.
  • Gaynor PT. (1996) Biomembrane electropermeabilization improvements. Lille, France: International Union of Radio Science 25th General Assembly, 28 Aug 1996.
Intellectual Property
  • Gaynor PT., Hughes JF., McKechnie MT. and Swingler J. (2004) Method for apparatus for controlling and removing dust and other particles from a material or for dispensing or delivering charged particles to a surface.Patent No. ZL 97181660.3.
  • Gaynor PT., Hughes JF., Swingler J. and McKechnie MT. (2004) Dust Control.Patent No. 0 010 391.
  • McKechnie MT., Gaynor PT., Hughes JF. and Swingler J. (2004) Method for controlling and removing dust and other particles from a material.Patent No. 6761773.
  • Gaynor PT., Hughes JF., Swingler J. and McKechnie MT. (2003) Dust Control.Patent No. MX215737.
  • Hughes JF., Gaynor PT., Swingler J. and McKechnie MT. (2003) Method for controlling and removing dust and other particles from a material.Patent No. EP 0 942 680 B1.

Review and Refereeing

Displaying all items.
  • Biophysical Journal ( 2006 - 2023)
  • IEEE Medical and Biological Engineering Magazine ( 2000 - 2023)
  • IEEE Medical and Biological Engineering Magazine ( 2000 - 2005)
  • IEEE Transactions on Circuits and Systems ( 2000 - 2011)
  • IEEE Transactions on Circuits and Systems ( 2000 - 2005)
  • Institute of Physics Physiological Measurement. ( 2007 - 2023)
  • Journal of Electrostatics ( 1998 - 2011)
  • Journal of Electrostatics ( 2000 - 2005)
  • Journal of Physics D - Applied Physics ( 2005 - 2023)
  • Lab on a Chip - Miniaturisation for Chemistry and Biology ( 2007 - 2023)
  • Medical and Biological Engineering and Computing ( 1998 - 2011)
  • Medical and Biological Engineering and Computing ( 2000 - 2005)
  • Physics in Medicine and Biology ( 2007 - 2023)

Affiliations

  • IEEE (Professional Organisation): Member (MIEEE)
  • New Zealand Geothermal Association (Professional Organisation): Member

Research Groups

  • Power Electronics Research Group (PERG)
  • Power Systems Group
  • The University of Canterbury Rose Centre for Stroke Recovery and Research at St George’s Medical Centre

Future Research

  • New applications for electroporation
  • Bio-feedback medical device for swallowing rehabilitation
  • Rural electric vehicle development
  • Electric vehicle multi-level inverter development
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